5FMW

The poly-C9 component of the Complement Membrane Attack Complex

Summary for 5FMW

Entry DOI	10.2210/pdb5fmw/pdb
EMDB information	3235
Descriptor	POLYC9 (1 entity in total)
Functional Keywords	structural protein, pore-forming protein, complement, c9, macpf
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Secreted : P02748
Total number of polymer chains	22
Total formula weight	1266823.16
Authors	Dudkina, N.V.,Spicer, B.A.,Reboul, C.F.,Conroy, P.J.,Lukoyanova, N.,Elmlund, H.,Law, R.H.P.,Ekkel, S.M.,Kondos, S.C.,Goode, R.J.A.,Ramm, G.,Whisstock, J.C.,Saibil, H.R.,Dunstone, M.A. (deposition date: 2015-11-10, release date: 2016-02-17, Last modification date: 2017-08-02)
Primary citation	Dudkina, N.V.,Spicer, B.A.,Reboul, C.F.,Conroy, P.J.,Lukoyanova, N.,Elmlund, H.,Law, R.H.P.,Ekkel, S.M.,Kondos, S.C.,Goode, R.J.A.,Ramm, G.,Whisstock, J.C.,Saibil, H.R.,Dunstone, M.A. Structure of the Poly-C9 Component of the Complement Membrane Attack Complex Nat.Commun., 7:10588-, 2016 Cited by PubMed: 26841934 DOI: 10.1038/NCOMMS10588 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (6.7 Å)

Structure validation