6RSY

The complex between TCR a7b2 and human Class I MHC HLA-A0201-WT1 with the bound RMFPNAPYL peptide.

Summary for 6RSY

• Entry DOI: 10.2210/pdb6rsy/pdb
• Descriptor: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ARG-MET-PHE-PRO-ASN-ALA-PRO-TYR-LEU, ... (7 entities in total)
• Functional Keywords: mhc class i antigen- tcr - peptide complex, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 10
• Total formula weight: 192377.98

Authors

Srikannathasan, V.,Robinson, R.A. (deposition date: 2019-05-22, release date: 2020-04-15, Last modification date: 2020-05-13)

• Primary citation: Holland, C.J.,Crean, R.M.,Pentier, J.M.,de Wet, B.,Lloyd, A.,Srikannathasan, V.,Lissin, N.,Lloyd, K.A.,Blicher, T.H.,Conroy, P.J.,Hock, M.,Pengelly, R.J.,Spinner, T.E.,Cameron, B.,Potter, E.A.,Jeyanthan, A.,Molloy, P.E.,Sami, M.,Aleksic, M.,Liddy, N.,Robinson, R.A.,Harper, S.,Lepore, M.,Pudney, C.R.,van der Kamp, M.W.,Rizkallah, P.J.,Jakobsen, B.K.,Vuidepot, A.,Cole, D.K.; Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA.; J.Clin.Invest., 130:2673-2688, 2020; PubMed: 32310221; DOI: 10.1172/JCI130562

Experimental method

X-RAY DIFFRACTION (2.95 Å)