6RSY
The complex between TCR a7b2 and human Class I MHC HLA-A0201-WT1 with the bound RMFPNAPYL peptide.
Summary for 6RSY
Entry DOI | 10.2210/pdb6rsy/pdb |
Descriptor | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ARG-MET-PHE-PRO-ASN-ALA-PRO-TYR-LEU, ... (7 entities in total) |
Functional Keywords | mhc class i antigen- tcr - peptide complex, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 192377.98 |
Authors | Srikannathasan, V.,Robinson, R.A. (deposition date: 2019-05-22, release date: 2020-04-15, Last modification date: 2020-05-13) |
Primary citation | Holland, C.J.,Crean, R.M.,Pentier, J.M.,de Wet, B.,Lloyd, A.,Srikannathasan, V.,Lissin, N.,Lloyd, K.A.,Blicher, T.H.,Conroy, P.J.,Hock, M.,Pengelly, R.J.,Spinner, T.E.,Cameron, B.,Potter, E.A.,Jeyanthan, A.,Molloy, P.E.,Sami, M.,Aleksic, M.,Liddy, N.,Robinson, R.A.,Harper, S.,Lepore, M.,Pudney, C.R.,van der Kamp, M.W.,Rizkallah, P.J.,Jakobsen, B.K.,Vuidepot, A.,Cole, D.K. Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA. J.Clin.Invest., 130:2673-2688, 2020 Cited by PubMed: 32310221DOI: 10.1172/JCI130562 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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