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6DLW

Complement component polyC9

Summary for 6DLW
Entry DOI10.2210/pdb6dlw/pdb
EMDB information7773
DescriptorComplement component C9, 2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose (3 entities in total)
Functional Keywordscomplement, pore, em, membrane, transmembrane, immune system
Biological sourceHomo sapiens (Human)
Total number of polymer chains22
Total formula weight1352075.08
Authors
Dunstone, M.A.,Spicer, B.A.,Law, R.H.P. (deposition date: 2018-06-03, release date: 2018-09-12, Last modification date: 2020-07-29)
Primary citationSpicer, B.A.,Law, R.H.P.,Caradoc-Davies, T.T.,Ekkel, S.M.,Bayly-Jones, C.,Pang, S.S.,Conroy, P.J.,Ramm, G.,Radjainia, M.,Venugopal, H.,Whisstock, J.C.,Dunstone, M.A.
The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Nat Commun, 9:3266-3266, 2018
Cited by
PubMed: 30111885
DOI: 10.1038/s41467-018-05717-0
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.9 Å)
Structure validation

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