5UGD
Protease Inhibitor
Summary for 5UGD
Entry DOI | 10.2210/pdb5ugd/pdb |
Related | 5UGG |
Descriptor | Plasminogen, Nalpha-[trans-4-(aminomethyl)cyclohexane-1-carbonyl]-N-octyl-O-[(pyridin-4-yl)methyl]-L-tyrosinamide (3 entities in total) |
Functional Keywords | fibrinolysis, yo, plasmin, inhibitor, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 28063.34 |
Authors | Law, R.H.P.,Wu, G.,Whisstock, J.C. (deposition date: 2017-01-08, release date: 2017-05-31, Last modification date: 2023-10-04) |
Primary citation | Law, R.H.P.,Wu, G.,Leung, E.W.W.,Hidaka, K.,Quek, A.J.,Caradoc-Davies, T.T.,Jeevarajah, D.,Conroy, P.J.,Kirby, N.M.,Norton, R.S.,Tsuda, Y.,Whisstock, J.C. X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors. Blood Adv, 1:766-771, 2017 Cited by PubMed: 29296720DOI: 10.1182/bloodadvances.2016004150 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.38 Å) |
Structure validation
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