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4Y1S

Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes

Summary for 4Y1S
Entry DOI10.2210/pdb4y1s/pdb
Related4Y1T
DescriptorPerforin-1, CALCIUM ION (3 entities in total)
Functional Keywordsperforin, c2 domain, calcium binding, immune system
Biological sourceMus musculus (house mouse)
Cellular locationCytoplasmic granule lumen: P10820
Total number of polymer chains1
Total formula weight16515.17
Authors
Conroy, P.J.,Yagi, H.,Whisstock, J.C.,Norton, R.S. (deposition date: 2015-02-09, release date: 2015-09-02, Last modification date: 2023-09-27)
Primary citationYagi, H.,Conroy, P.J.,Leung, E.W.,Law, R.H.,Trapani, J.A.,Voskoboinik, I.,Whisstock, J.C.,Norton, R.S.
Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes.
J.Biol.Chem., 290:25213-25226, 2015
Cited by
PubMed: 26306037
DOI: 10.1074/jbc.M115.668384
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.611 Å)
Structure validation

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