5UG6

Perforin C2 Domain - T431D

Summary for 5UG6

Entry DOI	10.2210/pdb5ug6/pdb
Related	5UG7
Descriptor	Perforin-1, IODIDE ION (3 entities in total)
Functional Keywords	c2, perforin, calcium, proteostasis, apoptosis
Biological source	Mus musculus (Mouse)
Total number of polymer chains	1
Total formula weight	16615.98
Authors	Law, R.H.P.,Conroy, P.J.,Voskoboinik, I.,Whisstock, J.C. (deposition date: 2017-01-07, release date: 2018-02-07, Last modification date: 2023-10-04)
Primary citation	Brennan, A.J.,Law, R.H.P.,Conroy, P.J.,Noori, T.,Lukoyanova, N.,Saibil, H.,Yagita, H.,Ciccone, A.,Verschoor, S.,Whisstock, J.C.,Trapani, J.A.,Voskoboinik, I. Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin. Cell Death Differ., 25:1517-1529, 2018 Cited by PubMed: 29416110 DOI: 10.1038/s41418-018-0057-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation