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8R08
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BU of 8r08 by Molmil
Cryo-EM structure of the cross-exon pre-B+AMPPNP complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, NHP2-like protein 1, N-terminally processed, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-31
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8QPE
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BU of 8qpe by Molmil
Cryo-EM Structure of Pre-B-like Complex (core part)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Microfibrillar-associated protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-01
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8QZS
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BU of 8qzs by Molmil
Cryo-EM structure of the cross-exon B-like complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Microfibrillar-associated protein 1, NHP2-like protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-29
公開日2024-05-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
6BI6
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BU of 6bi6 by Molmil
Solution NMR structure of uncharacterized protein YejG
分子名称: Uncharacterized protein YejG
著者Mohanty, B, Finn, T.J, Macindoe, I, Zhong, J, Patrick, W.M, Mackay, J.P.
登録日2017-11-01
公開日2018-11-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The uncharacterized bacterial protein YejG has the same architecture as domain III of elongation factor G.
Proteins, 87, 2019
8JWL
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BU of 8jwl by Molmil
The first purified state crystal structure of AKRtyl
分子名称: Aldo/keto reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Lin, S, Dai, S, Xiao, Z.
登録日2023-06-29
公開日2024-04-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A three-level regulatory mechanism of the aldo-keto reductase subfamily AKR12D.
Nat Commun, 15, 2024
8JWK
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BU of 8jwk by Molmil
The second purified state crystal structure of AKRtyl
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Aldo/keto reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Lin, S, Dai, S, Xiao, Z.
登録日2023-06-29
公開日2024-04-10
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献A three-level regulatory mechanism of the aldo-keto reductase subfamily AKR12D.
Nat Commun, 15, 2024
8XR4
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BU of 8xr4 by Molmil
Crystal structure of AKRtyl-NADP(H) complex
分子名称: Aldo/keto reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Lin, S, Dai, S, Xiao, Z.
登録日2024-01-06
公開日2024-04-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献A three-level regulatory mechanism of the aldo-keto reductase subfamily AKR12D.
Nat Commun, 15, 2024
8XR3
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BU of 8xr3 by Molmil
Crystal structure of AKRtyl-apo2
分子名称: Aldo/keto reductase
著者Lin, S, Dai, S, Xiao, Z.
登録日2024-01-06
公開日2024-04-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献A three-level regulatory mechanism of the aldo-keto reductase subfamily AKR12D.
Nat Commun, 15, 2024
8XR2
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BU of 8xr2 by Molmil
Crystal structure of AKRtyl-apo1
分子名称: Aldo/keto reductase
著者Lin, S, Dai, S, Xiao, Z.
登録日2024-01-06
公開日2024-04-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献A three-level regulatory mechanism of the aldo-keto reductase subfamily AKR12D.
Nat Commun, 15, 2024
8J0F
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BU of 8j0f by Molmil
GK tetramer with adjacent hooks at reaction state
分子名称: ADENOSINE-5'-DIPHOSPHATE, Delta-1-pyrroline-5-carboxylate synthase B, GAMMA-GLUTAMYL PHOSPHATE, ...
著者Zhang, T, Guo, C.J, Liu, J.L.
登録日2023-04-10
公開日2024-04-17
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Dynamic Arabidopsis P5CS filament facilitates substrate channelling.
Nat.Plants, 2024
8WYF
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BU of 8wyf by Molmil
Cryo-EM structure of DSR2-DSAD1-NAD+ (partial) complex
分子名称: Bacillus phage SPbeta DSAD1 protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2 family protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8WYC
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BU of 8wyc by Molmil
Cryo-EM structure of DSR2 (H171A)-tube-NAD+ (partial) complex
分子名称: Bacillus phage SPR Tube protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2-like domain-containing protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8WY8
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BU of 8wy8 by Molmil
Cryo-EM structure of DSR2 apo complex
分子名称: SIR2 family protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8WYB
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BU of 8wyb by Molmil
Cryo-EM structure of DSR2 (H171A)-tube-NAD+ complex
分子名称: Bacillus phage SPR Tube protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2-like domain-containing protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8Y2H
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BU of 8y2h by Molmil
GK tetramer of AtP5CS1 filament with adjacent hooks, reaction state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Delta-1-pyrroline-5-carboxylate synthase A
著者Zhang, T, Guo, C.J, Liu, J.L.
登録日2024-01-26
公開日2024-06-05
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Dynamic Arabidopsis P5CS filament facilitates substrate channelling.
Nat.Plants, 2024
8KG5
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BU of 8kg5 by Molmil
Prefusion RSV F Bound to Lonafarnib and D25 Fab
分子名称: 4-{2-[4-(3,10-DIBROMO-8-CHLORO-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERIDIN-1-YL]-2-OXOETHYL}PIPERIDINE-1-CARBOXAMIDE, D25 heavy chain, D25 light chain, ...
著者Yang, Q, Xue, B, Liu, F, Peng, W, Chen, X.
登録日2023-08-17
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein.
Signal Transduct Target Ther, 9, 2024
4XWY
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BU of 4xwy by Molmil
Crystal structure of human sepiapterin reductase in complex with an N-acetylserotinin analogue
分子名称: N-[2-(5-hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ...
著者Johnsson, K, Hovius, R, Gorszka, K.I, Pojer, F.
登録日2015-01-29
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway.
Neuron, 86, 2015
8JWO
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BU of 8jwo by Molmil
Crystal structure of AKRtyl-tylosin complex
分子名称: Aldo/keto reductase, TYLOSIN
著者Lin, S, Dai, S, Xiao, Z.
登録日2023-06-29
公開日2024-04-10
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献A three-level regulatory mechanism of the aldo-keto reductase subfamily AKR12D.
Nat Commun, 15, 2024
8JWN
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BU of 8jwn by Molmil
Crystal structure of AKRtyl-NADPH complex
分子名称: Aldo/keto reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Lin, S, Dai, S, Xiao, Z.
登録日2023-06-29
公開日2024-04-10
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献A three-level regulatory mechanism of the aldo-keto reductase subfamily AKR12D.
Nat Commun, 15, 2024
8JWM
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BU of 8jwm by Molmil
Crystal structure of AKRtyl-NADP-tylosin complex
分子名称: Aldo/keto reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TYLOSIN
著者Lin, S, Dai, S, Xiao, Z.
登録日2023-06-29
公開日2024-04-10
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献A three-level regulatory mechanism of the aldo-keto reductase subfamily AKR12D.
Nat Commun, 15, 2024
6AEI
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BU of 6aei by Molmil
Cryo-EM structure of the receptor-activated TRPC5 ion channel
分子名称: 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ...
著者Duan, J, Li, Z, Li, J, Zhang, J.
登録日2018-08-05
公開日2019-08-07
最終更新日2019-08-14
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Cryo-EM structure of TRPC5 at 2.8- angstrom resolution reveals unique and conserved structural elements essential for channel function.
Sci Adv, 5, 2019
5Y2F
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BU of 5y2f by Molmil
Human SIRT6 in complex with allosteric activator MDL-801
分子名称: 5-[[3,5-bis(chloranyl)phenyl]sulfonylamino]-2-[(5-bromanyl-4-fluoranyl-2-methyl-phenyl)sulfamoyl]benzoic acid, 9-mer peptide QTARKSTGG, DI(HYDROXYETHYL)ETHER, ...
著者Zhang, J, Huang, Z, Song, K.
登録日2017-07-25
公開日2018-11-07
最終更新日2018-11-28
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Identification of a cellularly active SIRT6 allosteric activator.
Nat. Chem. Biol., 14, 2018
1LYP
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BU of 1lyp by Molmil
THE SOLUTION STRUCTURE OF THE ACTIVE DOMAIN OF CAP18: A LIPOPOLYSACCHARIDE BINDING PROTEIN FROM RABBIT LEUKOCYTES
分子名称: CAP18
著者Chen, C, Huang, T.-H.
登録日1995-01-12
公開日1995-03-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure of the active domain of CAP18--a lipopolysaccharide binding protein from rabbit leukocytes.
FEBS Lett., 370, 1995
8OK4
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BU of 8ok4 by Molmil
Variant Surface Glycoprotein VSG11wt-Oil
分子名称: Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Zeelen, J.P, Stebbins, C.E, Aresta-Branco, F, Foti, K.
登録日2023-03-27
公開日2023-09-13
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
8ONH
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BU of 8onh by Molmil
Variant Surface Glycoprotein VSG11wt-Oil
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein, alpha-D-glucopyranose, ...
著者Zeelen, J.P, Stebbins, C.E, Foti, K, Gkeka, A, Vlachou, E.P.
登録日2023-04-03
公開日2023-09-13
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023

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