8JWM

Crystal structure of AKRtyl-NADP-tylosin complex

Summary for 8JWM

Entry DOI	10.2210/pdb8jwm/pdb
Descriptor	Aldo/keto reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TYLOSIN, ... (4 entities in total)
Functional Keywords	complex, oxidoreductase
Biological source	Streptomyces xinghaiensis
Total number of polymer chains	8
Total formula weight	320080.56
Authors	Lin, S.,Dai, S.,Xiao, Z. (deposition date: 2023-06-29, release date: 2024-04-10)
Primary citation	Xiao, Z.,Zha, J.,Yang, X.,Huang, T.,Huang, S.,Liu, Q.,Wang, X.,Zhong, J.,Zheng, J.,Liang, R.,Deng, Z.,Zhang, J.,Lin, S.,Dai, S. A three-level regulatory mechanism of the aldo-keto reductase subfamily AKR12D. Nat Commun, 15:2128-2128, 2024 Cited by PubMed: 38459030 DOI: 10.1038/s41467-024-46363-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.93 Å)

Structure validation