8JWO

Crystal structure of AKRtyl-tylosin complex

Summary for 8JWO

Entry DOI	10.2210/pdb8jwo/pdb
Descriptor	Aldo/keto reductase, TYLOSIN (3 entities in total)
Functional Keywords	complex, oxidoreductase
Biological source	Streptomyces xinghaiensis
Total number of polymer chains	16
Total formula weight	630098.85
Authors	Lin, S.,Dai, S.,Xiao, Z. (deposition date: 2023-06-29, release date: 2024-04-10)
Primary citation	Xiao, Z.,Zha, J.,Yang, X.,Huang, T.,Huang, S.,Liu, Q.,Wang, X.,Zhong, J.,Zheng, J.,Liang, R.,Deng, Z.,Zhang, J.,Lin, S.,Dai, S. A three-level regulatory mechanism of the aldo-keto reductase subfamily AKR12D. Nat Commun, 15:2128-2128, 2024 Cited by PubMed: 38459030 DOI: 10.1038/s41467-024-46363-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation