6AEI

Cryo-EM structure of the receptor-activated TRPC5 ion channel

Summary for 6AEI

Entry DOI	10.2210/pdb6aei/pdb
EMDB information	9615
Descriptor	Short transient receptor potential channel 5, SODIUM ION, CHOLESTEROL HEMISUCCINATE, ... (4 entities in total)
Functional Keywords	cryo-em, mouse trpc5, ion channel, membrane protein
Biological source	Mus musculus (Mouse)
Total number of polymer chains	4
Total formula weight	360272.11
Authors	Duan, J.,Li, Z.,Li, J.,Zhang, J. (deposition date: 2018-08-05, release date: 2019-08-07, Last modification date: 2019-08-14)
Primary citation	Duan, J.,Li, J.,Chen, G.L.,Ge, Y.,Liu, J.,Xie, K.,Peng, X.,Zhou, W.,Zhong, J.,Zhang, Y.,Xu, J.,Xue, C.,Liang, B.,Zhu, L.,Liu, W.,Zhang, C.,Tian, X.L.,Wang, J.,Clapham, D.E.,Zeng, B.,Li, Z.,Zhang, J. Cryo-EM structure of TRPC5 at 2.8- angstrom resolution reveals unique and conserved structural elements essential for channel function. Sci Adv, 5:-, 2019 Cited by PubMed: 31355338 DOI: 10.1126/sciadv.aaw7935 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.89 Å)

Structure validation