6AEI

Cryo-EM structure of the receptor-activated TRPC5 ion channel

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Short transient receptor potential channel 5	polymer	765	88903.7	4	UniProt (Q9QX29) Pfam (PF12796) Pfam (PF00023) Pfam (PF08344) Pfam (PF00520)	Mus musculus (Mouse)	TrpC5,Capacitative calcium entry channel 2,CCE2,Transient receptor protein 5,mTRP5,Trp-related protein 5
2	E, F, I, L, O (A, B, C, D)	SODIUM ION	non-polymer		23.0	5	Chemie (NA) PubChem (923)
3	G, J, M, P (A, B, C, D)	CHOLESTEROL HEMISUCCINATE	non-polymer		486.7	4	Chemie (Y01) PubChem (65082) PubChem (363416) PubChem (500055) PubChem (13301926) PubChem (13301927) PubChem (16219150) PubChem (22210610) PubChem (45489984) PubChem (57163942) PubChem (89891013) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (11969853) PubChem (137392566) PubChem (137496323) PubChem (155804219) PubChem (169132514) PubChem (60078761) PubChem (73440805) PubChem (99567469) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (124914595) PubChem (124914596) PubChem (131705526) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028)
4	H, K, N, Q (A, B, C, D)	2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE	non-polymer		648.9	4	Chemie (LPP) PubChem (3099) PubChem (446066) PubChem (11061290)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	355614.7
Non-Polymers*	Number of molecules	13
	Total formula weight	4657.4
All*	Total formula weight	360272.1

*Water molecules are not included.