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6AEI

Cryo-EM structure of the receptor-activated TRPC5 ion channel

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Short transient receptor potential channel 5polymer76588903.74UniProt (Q9QX29)
Pfam (PF12796)
Pfam (PF00023)
Pfam (PF08344)
Pfam (PF00520)
Mus musculus (Mouse)TrpC5,Capacitative calcium entry channel 2,CCE2,Transient receptor protein 5,mTRP5,Trp-related protein 5
2E, F, I, L, O
(A, B, C, D)
SODIUM IONnon-polymer23.05Chemie (NA)
3G, J, M, P
(A, B, C, D)
CHOLESTEROL HEMISUCCINATEnon-polymer486.74Chemie (Y01)
4H, K, N, Q
(A, B, C, D)
2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATEnon-polymer648.94Chemie (LPP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight355614.7
Non-Polymers*Number of molecules13
Total formula weight4657.4
All*Total formula weight360272.1
*Water molecules are not included.

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PDB entries from 2025-08-27

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