8XR4

Crystal structure of AKRtyl-NADP(H) complex

Summary for 8XR4

• Entry DOI: 10.2210/pdb8xr4/pdb
• Descriptor: Aldo/keto reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
• Functional Keywords: oxidoreductase
• Biological source: Streptomyces xinghaiensis
• Total number of polymer chains: 8
• Total formula weight: 296296.86

Authors

Lin, S.,Dai, S.,Xiao, Z. (deposition date: 2024-01-06, release date: 2024-04-10)

• Primary citation: Xiao, Z.,Zha, J.,Yang, X.,Huang, T.,Huang, S.,Liu, Q.,Wang, X.,Zhong, J.,Zheng, J.,Liang, R.,Deng, Z.,Zhang, J.,Lin, S.,Dai, S.; A three-level regulatory mechanism of the aldo-keto reductase subfamily AKR12D; Nat Commun, 15:2128-, 2024; DOI: 10.1038/s41467-024-46363-z

Experimental method

X-RAY DIFFRACTION (1.94 Å)