8ONH

Variant Surface Glycoprotein VSG11wt-Oil

Summary for 8ONH

• Entry DOI: 10.2210/pdb8onh/pdb
• Descriptor: Variant surface glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• Functional Keywords: variant surface glycoprotein suramin trypanosomiasis drug resistance glycosylation, membrane protein
• Biological source: Trypanosoma brucei brucei
• Total number of polymer chains: 18
• Total formula weight: 809348.63

Authors

Zeelen, J.P.,Stebbins, C.E.,Foti, K.,Gkeka, A.,Vlachou, E.P. (deposition date: 2023-04-03, release date: 2023-09-13)

• Primary citation: Dakovic, S.,Zeelen, J.P.,Gkeka, A.,Chandra, M.,van Straaten, M.,Foti, K.,Zhong, J.,Vlachou, E.P.,Aresta-Branco, F.,Verdi, J.P.,Papavasiliou, F.N.,Stebbins, C.E.; A structural classification of the variant surface glycoproteins of the African trypanosomey.; Plos Negl Trop Dis, 17:e0011621-e0011621, 2023; PubMed: 37656766; DOI: 10.1371/journal.pntd.0011621

Experimental method

X-RAY DIFFRACTION (2.59 Å)