6ICI
 
 | | Crystal structure of human MICAL3 | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, [F-actin]-monooxygenase MICAL3 | | Authors: | Hwang, K.Y, Kim, J.S. | | Deposit date: | 2018-09-06 | | Release date: | 2020-03-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and kinetic insights into flavin-containing monooxygenase and calponin-homology domains in human MICAL3.
Iucrj, 7, 2020
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4Y0C
 | | The structure of Arabidopsis ClpT2 | | Descriptor: | CHLORIDE ION, Clp protease-related protein At4g12060, chloroplastic, ... | | Authors: | Kimber, M.S, Schultz, L. | | Deposit date: | 2015-02-05 | | Release date: | 2015-05-13 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.992 Å) | | Cite: | Structures, Functions, and Interactions of ClpT1 and ClpT2 in the Clp Protease System of Arabidopsis Chloroplasts.
Plant Cell, 27, 2015
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4Y0B
 | | The structure of Arabidopsis ClpT1 | | Descriptor: | CHLORIDE ION, Double Clp-N motif protein | | Authors: | Kimber, M.S, Schultz, L. | | Deposit date: | 2015-02-05 | | Release date: | 2015-05-13 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structures, Functions, and Interactions of ClpT1 and ClpT2 in the Clp Protease System of Arabidopsis Chloroplasts.
Plant Cell, 27, 2015
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8ZBH
 | | Crystal structure of TEAD3 YAP binding domain with compound 3 | | Descriptor: | 1-[7-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-isoquinolin-2-yl]propan-1-one, Transcriptional enhancer factor TEF-5 | | Authors: | Yoo, Y, Kim, H. | | Deposit date: | 2024-04-26 | | Release date: | 2025-04-16 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Pan-Transcriptional Enhanced Associated Domain Palmitoylation Pocket Covalent Inhibitor.
J.Med.Chem., 67, 2024
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8ZBG
 | | Crystal structure of TEAD3 YAP binding domain with compound 15 | | Descriptor: | (2~{R})-2-fluoranyl-1-[7-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-isoquinolin-2-yl]propan-1-one, Transcriptional enhancer factor TEF-5 | | Authors: | Yoo, Y, Kim, H. | | Deposit date: | 2024-04-26 | | Release date: | 2025-04-16 | | Method: | X-RAY DIFFRACTION (2.67 Å) | | Cite: | Pan-Transcriptional Enhanced Associated Domain Palmitoylation Pocket Covalent Inhibitor.
J.Med.Chem., 67, 2024
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7DR4
 | | Complex of anti-human IL-2 antibody and human IL-2 | | Descriptor: | Interleukin-2, anti-human IL-2 antibody, mouse Ig G, ... | | Authors: | Kim, M.S, Kim, J.E. | | Deposit date: | 2020-12-25 | | Release date: | 2021-04-14 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Crystal structure of human interleukin-2 in complex with TCB2, a new antibody-drug candidate with antitumor activity.
Oncoimmunology, 10, 2021
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2NBP
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2NBO
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7DXN
 | | Plant growth-promoting factor YxaL from Bacillus velezensis | | Descriptor: | CHLORIDE ION, Membrane associated protein kinase with beta-propeller domain, pyrrolo-quinoline quinone beta-propeller repeat | | Authors: | Baek, Y, Ha, N.-C. | | Deposit date: | 2021-01-19 | | Release date: | 2022-01-19 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of the plant growth-promoting factor YxaL from the rhizobacterium Bacillus velezensis and its application to protein engineering.
Acta Crystallogr D Struct Biol, 78, 2022
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2K6P
 | | Solution Structure of hypothetical protein, HP1423 | | Descriptor: | Uncharacterized protein HP_1423 | | Authors: | Kim, J, Park, S, Lee, K, Son, W, Sohn, N, Lee, B. | | Deposit date: | 2008-07-15 | | Release date: | 2009-06-16 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of hypothetical protein HP1423 (Y1423_HELPY) reveals the presence of alphaL motif related to RNA binding
Proteins, 75, 2009
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2MXD
 | | Solution structure of VPg of porcine sapovirus | | Descriptor: | Viral protein genome-linked | | Authors: | Kim, J, Hwang, H, Min, H, Yun, H, Cho, K, Pelton, J.G, Wemmer, D.E, Lee, C. | | Deposit date: | 2014-12-24 | | Release date: | 2015-04-15 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the porcine sapovirus VPg core reveals a stable three-helical bundle with a conserved surface patch.
Biochem.Biophys.Res.Commun., 459, 2015
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3RUJ
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3RUI
 | | Crystal structure of Atg7C-Atg8 complex | | Descriptor: | Autophagy-related protein 8, Ubiquitin-like modifier-activating enzyme ATG7, ZINC ION | | Authors: | Hong, S.B, Kim, B.W, Song, H.K. | | Deposit date: | 2011-05-05 | | Release date: | 2011-11-23 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.906 Å) | | Cite: | Insights into noncanonical E1 enzyme activation from the structure of autophagic E1 Atg7 with Atg8.
Nat.Struct.Mol.Biol., 18, 2011
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5K8Q
 | | Crystal Structure of Calcium-loaded Calmodulin in complex with STRA6 CaMBP2-site peptide. | | Descriptor: | CALCIUM ION, Calmodulin, IMIDAZOLE, ... | | Authors: | Stowe, S.D, Clarke, O.B, Cavalier, M.C, Godoy-Ruiz, R, Mancia, F, Weber, D.J. | | Deposit date: | 2016-05-30 | | Release date: | 2016-08-24 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.739 Å) | | Cite: | Structure of the STRA6 receptor for retinol uptake.
Science, 353, 2016
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4WG3
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4WG5
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4WG4
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8P82
 | | Cryo-EM structure of dimeric UBR5 | | Descriptor: | E3 ubiquitin-protein ligase UBR5, ZINC ION | | Authors: | Aguirre, J.D, Kater, L, Kempf, G, Cavadini, S, Thoma, N.H. | | Deposit date: | 2023-05-31 | | Release date: | 2023-06-14 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.36 Å) | | Cite: | UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
Mol.Cell, 83, 2023
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8P83
 | | Cryo-EM structure of full-length human UBR5 (homotetramer) | | Descriptor: | E3 ubiquitin-protein ligase UBR5 | | Authors: | Aguirre, J.D, Kater, L, Kempf, G, Cavadini, S, Thoma, N.H. | | Deposit date: | 2023-05-31 | | Release date: | 2023-06-14 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (3.87 Å) | | Cite: | UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
Mol.Cell, 83, 2023
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6J10
 | | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly | | Descriptor: | 6-cyclohexyl-4-methyl-1-oxidanyl-pyridin-2-one, Capsid protein | | Authors: | Park, S, Jin, M.S, Cho, Y, Kang, J, Kim, S, Park, M, Park, H, Kim, J, Park, S, Hwang, J, Kim, Y, Kim, Y.J. | | Deposit date: | 2018-12-27 | | Release date: | 2019-04-17 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly.
Nat Commun, 10, 2019
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5CRO
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8PM2
 | | Structure of the murine trace amine-associated receptor TAAR7f bound to N,N-dimethylcyclohexylamine (DMCH) in complex with mini-Gs trimeric G protein | | Descriptor: | CHOLESTEROL HEMISUCCINATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Gusach, A, Lee, Y, Edwards, P.C, Huang, F, Weyand, S.N, Tate, C.G. | | Deposit date: | 2023-06-28 | | Release date: | 2023-08-09 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (2.92 Å) | | Cite: | Molecular recognition of an aversive odorant by the murine trace amine-associated receptor TAAR7f.
Biorxiv, 2023
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5Y7X
 | | Human Peroxisome proliferator-activated receptor (PPAR) delta in complexed with a potent and selective agonist | | Descriptor: | 2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-selenazol-5-yl]methylsulfanyl]phenoxy]ethanoic acid, CHLORIDE ION, POTASSIUM ION, ... | | Authors: | Kim, H.L, Chin, J.W, Cho, S.J, Song, J.Y, Yoon, H.S, Bae, J.H. | | Deposit date: | 2017-08-18 | | Release date: | 2018-08-01 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.699 Å) | | Cite: | Highly potent and selective PPAR delta agonist reverses memory deficits in mouse models of Alzheimer's disease.
Theranostics, 14, 2024
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4KV2
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8D73
 | | Crystal Structure of EGFR LRTM with compound 7 | | Descriptor: | (3S,4R)-3-fluoro-1-(4-{[4-(methylamino)-1-(propan-2-yl)pyrido[3,4-d]pyridazin-7-yl]amino}pyrimidin-2-yl)piperidin-4-ol, Epidermal growth factor receptor, GLYCEROL | | Authors: | Kim, J.L. | | Deposit date: | 2022-06-07 | | Release date: | 2022-07-27 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Discovery of BLU-945, a Reversible, Potent, and Wild-Type-Sparing Next-Generation EGFR Mutant Inhibitor for Treatment-Resistant Non-Small-Cell Lung Cancer.
J.Med.Chem., 65, 2022
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