8PM2

Structure of the murine trace amine-associated receptor TAAR7f bound to N,N-dimethylcyclohexylamine (DMCH) in complex with mini-Gs trimeric G protein

Summary for 8PM2

• Entry DOI: 10.2210/pdb8pm2/pdb
• EMDB information: 17756
• Descriptor: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• Functional Keywords: trace-amine associated receptor, taar, mtaar7f, gpcr, receptor, g protein, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 132705.17

Authors

Gusach, A.,Lee, Y.,Edwards, P.C.,Huang, F.,Weyand, S.N.,Tate, C.G. (deposition date: 2023-06-28, release date: 2023-08-09)

• Primary citation: Gusach, A.,Lee, Y.,Khoshgrudi, A.N.,Mukhaleva, E.,Ma, N.,Koers, E.J.,Chen, Q.,Edwards, P.C.,Huang, F.,Kim, J.,Mancia, F.,Verprintsev, D.B.,Vaidehi, N.,Weyand, S.N.,Tate, C.G.; Molecular recognition of an aversive odorant by the murine trace amine-associated receptor TAAR7f.; Biorxiv, 2023; PubMed: 37461561; DOI: 10.1101/2023.07.07.547762

Experimental method

ELECTRON MICROSCOPY (2.92 Å)