7DR4
Complex of anti-human IL-2 antibody and human IL-2
Summary for 7DR4
Entry DOI | 10.2210/pdb7dr4/pdb |
Descriptor | anti-human IL-2 antibody, mouse Ig G, heavy chain, anti-human IL-2 antibody, mouse Ig G, kappa chain, Interleukin-2, ... (4 entities in total) |
Functional Keywords | complex, human il-2, antibody, tcell, protein binding, immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 12 |
Total formula weight | 252251.56 |
Authors | |
Primary citation | Kim, J.,Lee, J.Y.,Park, S.Y.,Lee, Y.J.,Kim, M.S. Crystal structure of human interleukin-2 in complex with TCB2, a new antibody-drug candidate with antitumor activity. Oncoimmunology, 10:1899671-1899671, 2021 Cited by PubMed: 33796411DOI: 10.1080/2162402X.2021.1899671 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.49 Å) |
Structure validation
Download full validation report