7DR4

Complex of anti-human IL-2 antibody and human IL-2

Summary for 7DR4

• Entry DOI: 10.2210/pdb7dr4/pdb
• Descriptor: anti-human IL-2 antibody, mouse Ig G, heavy chain, anti-human IL-2 antibody, mouse Ig G, kappa chain, Interleukin-2, ... (4 entities in total)
• Functional Keywords: complex, human il-2, antibody, tcell, protein binding, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 12
• Total formula weight: 252251.56

Authors

Kim, M.S.,Kim, J.E. (deposition date: 2020-12-25, release date: 2021-04-14, Last modification date: 2023-11-29)

• Primary citation: Kim, J.,Lee, J.Y.,Park, S.Y.,Lee, Y.J.,Kim, M.S.; Crystal structure of human interleukin-2 in complex with TCB2, a new antibody-drug candidate with antitumor activity.; Oncoimmunology, 10:1899671-1899671, 2021; PubMed: 33796411; DOI: 10.1080/2162402X.2021.1899671

Experimental method

X-RAY DIFFRACTION (2.49 Å)