4WG5

Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1647

Summary for 4WG5

• Entry DOI: 10.2210/pdb4wg5/pdb
• Related: 4WG3 4WG5
• Descriptor: Calmodulin-domain protein kinase 1, 5-amino-3-[7-(cyclobutyloxy)quinolin-3-yl]-1-cyclohexyl-1H-pyrazole-4-carboxamide (3 entities in total)
• Functional Keywords: serine/threonine protein kinase, transferase, calcium-binding, atp-binding, bumped kinase inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Toxoplasma gondii
• Total number of polymer chains: 1
• Total formula weight: 55632.41

Authors

Merritt, E.A. (deposition date: 2014-09-17, release date: 2014-10-15, Last modification date: 2023-12-27)

• Primary citation: Merritt, E.A.,Maly, D.J.,Ojo, K.K.,Zhang, Z.,Fan, E.,Van Voorhis, W.C.; Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1647; to be published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)