2CIK

Insights Into Crossreactivity in Human Allorecognition: The Structure of HLA-B35011 Presenting an Epitope derived from Cytochrome P450.

Summary for 2CIK

Related1A1M 1A1N 1A1O 1A6Z 1A9B 1A9E 1AGB 1AGC 1AGD 1AGE 1AGF 1AKJ 1AO7 1B0G 1B0R 1BD2 1C16 1CE6 1CG9 1DE4 1DUY 1DUZ 1E27 1E28 1EEY 1EEZ 1EFX 1EXU 1GZP 1GZQ 1HHG 1HHH 1HHI 1HHJ 1HHK 1HLA 1HSA 1HSB 1I1F 1I1Y 1I4F 1I7R 1I7T 1I7U 1IM3 1IM9 1JF1 1JGD 1JGE 1JHT 1JNJ 1K5N 1KPR 1KTL 1LDS 1LP9 1M05 1M6O 1MHE 1MI5 1N2R 1OF2 1OGA 1OGT 1ONQ 1P7Q 1PY4 1Q94 1QEW 1QLF 1QQD 1QR1 1QRN 1QSE 1QSF 1QVO 1R3H 1S9W 1S9X 1S9Y 1SYS 1SYV 1TMC 1TVB 1TVH 1UQS 1UR7 1UXS 1UXW 1VGK 1W0V 1W0W 1W72 1X7Q 1XH3 1XR8 1XR9 1XZ0 1YDP 1YPZ 1ZS8 1ZSD 1ZT4 2A83 2AK4 2AV7 2AXF 2AXG 2BCK 2BNQ 2BNR 2BSR 2BSS 2BST 2BSU 2BSV 2BVQ 2C7U 2CLR 2D31 2F74 2F8O 2HLA 3HLA
DescriptorHLA CLASS I HISTOCOMPATIBILITY ANTIGEN B-35 ALPHA CHAIN, BETA-2-MICROGLOBULIN, PEPTIDE, ... (5 entities in total)
Functional Keywordsimmune system/peptide, antigen-peptide complex, major histocompatibility antigen, human, mhc, hla, hla-b3501, ebv, allo-ligand, glycoprotein, immune response, membrane, mhc i, polymorphism, transmembrane, immunoglobulin domain, pyrrolidone carboxylic acid, immune system-peptide complex
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationMembrane; Single-pass type I membrane protein P30685
Secreted P61769
Total number of polymer chains3
Total molecular weight44991.95
Authors
Hourigan, C.S.,Harkiolaki, M.,Peterson, N.A.,Bell, J.I.,Jones, E.Y.,O'Callaghan, C.A. (deposition date: 2006-03-22, release date: 2006-10-25, Last modification date: 2011-07-13)
Primary citation
Hourigan, C.S.,Harkiolaki, M.,Peterson, N.A.,Bell, J.I.,Jones, E.Y.,O'Callaghan, C.A.
The Structure of the Human Allo-Ligand Hla-B3501 in Complex with a Cytochrome P450 Peptide: Steric Hindrance Influences Tcr Allo-Recognition.
Eur.J.Immunol., 36:3288-, 2006
PubMed: 17109469 (PDB entries with the same primary citation)
DOI: 10.1002/EJI.200636234
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.75 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.231501.8%7.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution