Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2AV7

Crystal structure of HTLV-1 TAX peptide Bound to Human Class I MHC HLA-A2 with the K66A mutation in the heavy chain.

Summary for 2AV7
Entry DOI10.2210/pdb2av7/pdb
Related1DUY 1DUZ 2AV1
DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Trans-activating transcriptional regulatory peptide, ... (5 entities in total)
Functional Keywordstax peptide, mhc, mutated hla-a2, k66a., immune system
Biological sourceHomo sapiens (human)
More
Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted: P61769
Host nucleus (By similarity): P14079
Total number of polymer chains6
Total formula weight91333.35
Authors
Borbulevych, O.Y.,Baker, B.M. (deposition date: 2005-08-29, release date: 2005-10-18, Last modification date: 2023-08-23)
Primary citationGagnon, S.J.,Borbulevych, O.Y.,Davis-Harrison, R.L.,Baxter, T.K.,Clemens, J.R.,Armstrong, K.M.,Turner, R.V.,Damirjian, M.,Biddison, W.E.,Baker, B.M.
Unraveling a Hotspot for TCR Recognition on HLA-A2: Evidence Against the Existence of Peptide-independent TCR Binding Determinants.
J.Mol.Biol., 353:556-573, 2005
Cited by
PubMed: 16197958
DOI: 10.1016/j.jmb.2005.08.024
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.05 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon