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3UY6
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BU of 3uy6 by Molmil
BlaR1 sensor domain from Staphylococcus aureus with N439V mutation
Descriptor: GLYCEROL, Regulatory protein BlaR1, SULFATE ION
Authors:Baker, B.M, Borbulevych, O.Y.
Deposit date:2011-12-05
Release date:2012-02-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An amino acid position at crossroads of evolution of protein function: antibiotic sensor domain of BlaR1 protein from Staphylococcus aureus versus clasS D beta-lactamases
J.Biol.Chem., 287, 2012
8TBV
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BU of 8tbv by Molmil
Human Class I MHC HLA-A2 in complex with sorting nexin 24 (127-135) neoantigen KLSHQLVLL
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Arbuiso, A, Weiss, L.I, Brambley, C.A, Ma, J, Keller, G.L.J, Ayres, C.M, Baker, B.M.
Deposit date:2023-06-29
Release date:2024-01-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Accurate modeling of peptide-MHC structures with AlphaFold.
Structure, 32, 2024
8U9G
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BU of 8u9g by Molmil
Human Class I MHC HLA-A2 bound to sorting nexin 24 (127-135) neoantigen KLSHQLVLL
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
Authors:Arbuiso, A, Weiss, L.I, Brambley, C.A, Ma, J, Keller, G.L.J, Ayres, C.M, Baker, B.M.
Deposit date:2023-09-19
Release date:2024-01-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Accurate modeling of peptide-MHC structures with AlphaFold.
Structure, 32, 2024
8TBW
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BU of 8tbw by Molmil
Human Class I MHC HLA-A2 in complex with sorting nexin 24 (127-135) peptide KLSHQPVLL
Descriptor: Beta-2-microglobulin, HLA-A*02:01 alpha chain, NITRATE ION, ...
Authors:Arbuiso, A, Weiss, L.I, Brambley, C.A, Ma, J, Keller, G.L.J, Ayres, C.M, Baker, B.M.
Deposit date:2023-06-29
Release date:2024-01-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.081 Å)
Cite:Accurate modeling of peptide-MHC structures with AlphaFold.
Structure, 32, 2024
8FHU
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BU of 8fhu by Molmil
Structure of Pyruvate dehydrogenase phosphatase regulatory subunit epitope presented by H2-Dd
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-D alpha chain, ...
Authors:Custodio, J.M.F, Baker, B.M.
Deposit date:2022-12-15
Release date:2023-06-28
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structure of Pyruvate dehydrogenase phosphatase regulatory subunit neoepitope presented by H2-Dd
To Be Published
8FHL
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BU of 8fhl by Molmil
Structure of pyruvate dehydrogenase phosphatase regulatory subunit neoepitope presented by H2-Dd
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-D alpha chain, ...
Authors:Custodio, J.M.F, Baker, B.M.
Deposit date:2022-12-14
Release date:2023-06-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.194 Å)
Cite:Structure of Pyruvate dehydrogenase phosphatase regulatory subunit neoepitope presented by H2-Dd
To Be Published
8D5J
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BU of 8d5j by Molmil
The complex of Pre-mRNA-Processing Factor 19 (Prpf19) neoantigen KYLQVASHV Presented by H2-Kd
Descriptor: Beta-2-microglobulin, MHC class I heavy chain maturation peptide H-2K(D), Pre-mRNA-processing factor 19
Authors:Custodio, J.M.F, Baker, B.M.
Deposit date:2022-06-04
Release date:2022-07-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The complex of Pre-mRNA-Processing Factor 19 (Prpf19) neoantigen KYLQVASHV Presented by H2-Kd
To Be Published
8D5K
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BU of 8d5k by Molmil
The complex of Pre-mRNA-Processing Factor 19 (Prpf19) peptide KYLQVASHV Presented by H2-Kd
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-D alpha chain, ...
Authors:Custodio, J.M.F, Baker, B.M.
Deposit date:2022-06-05
Release date:2022-07-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.066 Å)
Cite:Structural and physical features that distinguish tumor-controlling from inactive cancer neoepitopes.
Proc.Natl.Acad.Sci.USA, 120, 2023
8D5F
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BU of 8d5f by Molmil
The complex of Gtf2b neoantigen TGAARFDEF Presented by H2-Dd
Descriptor: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
Authors:Custodio, J.M.F, Baker, B.M.
Deposit date:2022-06-04
Release date:2022-07-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural and physical features that distinguish tumor-controlling from inactive cancer neoepitopes.
Proc.Natl.Acad.Sci.USA, 120, 2023
8D5E
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BU of 8d5e by Molmil
The complex of Gtf2b Peptide TGAASFDEF Presented by H2-Dd
Descriptor: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
Authors:Custodio, J.M.F, Baker, B.M.
Deposit date:2022-06-04
Release date:2022-07-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structural and physical features that distinguish tumor-controlling from inactive cancer neoepitopes.
Proc.Natl.Acad.Sci.USA, 120, 2023
5JZI
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BU of 5jzi by Molmil
Crystal structure of 1406 TCR bound to HLA-A2 with HCV 1406-1415 antigen peptide
Descriptor: Beta-2-microglobulin, HCV1406 TCR alpha chain, HCV1406 TCR beta chain, ...
Authors:Wang, Y, Piepenbrink, K.H, Baker, B.M.
Deposit date:2016-05-16
Release date:2017-05-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:How an alloreactive T-cell receptor achieves peptide and MHC specificity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7RE8
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BU of 7re8 by Molmil
Class I MHC (HLA-A*02) presenting alpha fetoprotein peptide (AFP)
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, MHC class I antigen, ...
Authors:Dasgupta, M, Baker, B.M.
Deposit date:2021-07-12
Release date:2022-07-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma.
Sci Rep, 12, 2022
7RE9
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BU of 7re9 by Molmil
TCR mimic antibody (Fab fragment)
Descriptor: DI(HYDROXYETHYL)ETHER, Fab heavy chain, Fab light chain
Authors:Dasgupta, M, Baker, B.M.
Deposit date:2021-07-12
Release date:2022-07-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma.
Sci Rep, 12, 2022
7RE7
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BU of 7re7 by Molmil
TCR mimic antibody (Fab fragment) in complex with AFP/HLA-A*02
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, FORMIC ACID, ...
Authors:Dasgupta, M, Baker, B.M.
Deposit date:2021-07-12
Release date:2022-07-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.547 Å)
Cite:Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma.
Sci Rep, 12, 2022
7RRG
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BU of 7rrg by Molmil
Crystal structure of human 0606T1-2 TCR bound to HLA-A*03:01 in complex with a mutant PIK3CA peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Ma, J, Baker, B.M.
Deposit date:2021-08-09
Release date:2022-03-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Nat Med, 28, 2022
7RK7
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BU of 7rk7 by Molmil
The complex between TIL 1383i TCR and human Class I MHC HLA-A2 with the bound Tyrosinase(369-377)(N371D) nonameric peptide
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ...
Authors:Singh, N.K, Davancaze, L.M, Arbuiso, A, Weiss, L.I, Keller, G.L.J, Baker, B.M.
Deposit date:2021-07-22
Release date:2022-11-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:The complex between TIL 1383i TCR and human Class I MHC HLA-A2 with the bound Tyrosinase(369-377)(N371D) nonameric peptide
To Be Published
7U21
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BU of 7u21 by Molmil
Human Class I MHC HLA-A2 in complex with AVGSYVYSV peptide
Descriptor: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ...
Authors:Weiss, L.I, Baker, B.M.
Deposit date:2022-02-22
Release date:2022-06-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Physicochemical Heuristics for Identifying High Fidelity, Near-Native Structural Models of Peptide/MHC Complexes.
Front Immunol, 13, 2022
3D3V
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BU of 3d3v by Molmil
The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5(3,4-difluoroPhenylalanine)) peptide
Descriptor: A6 TCR alpha chain, A6 TCR beta chain, Beta-2-microglobulin, ...
Authors:Borbulevych, O.Y, Clemens, J.R, Baker, B.M.
Deposit date:2008-05-12
Release date:2009-06-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner.
Biochem.J., 423, 2009
3D39
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BU of 3d39 by Molmil
The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5(4-fluoroPhenylalanine)) peptide
Descriptor: A6 TCR alpha chain, A6 TCR beta chain, Beta-2-microglobulin, ...
Authors:Borbulevych, O.Y, Clemens, J.R, Baker, B.M.
Deposit date:2008-05-09
Release date:2009-06-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner
Biochem.J., 423, 2009
4ZDH
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BU of 4zdh by Molmil
Crystal structure of JKA6 TCR
Descriptor: Alpha chain of A6 T-cell receptor,T-cell receptor alpha chain C region, Beta chain of JKF6 T-cell receptor,Protein TRBV28
Authors:Singh, N.K, Hossain, M, Baker, B.M.
Deposit date:2015-04-17
Release date:2016-05-04
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.0984 Å)
Cite:Crystal structure of JKA6 TCR
To Be Published
7L1C
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BU of 7l1c by Molmil
Crystal structure of HLA-A*03:01 in complex with a mutant PIK3CA peptide
Descriptor: Beta-2-microglobulin, FORMIC ACID, GLYCEROL, ...
Authors:Ma, J, Baker, B.M.
Deposit date:2020-12-14
Release date:2022-03-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Nat Med, 28, 2022
7L1B
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BU of 7l1b by Molmil
Crystal structure of HLA-A*03:01 in complex with a wild-type PIK3CA peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Ma, J, Baker, B.M.
Deposit date:2020-12-14
Release date:2022-03-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Nat Med, 28, 2022
7L1D
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BU of 7l1d by Molmil
Crystal structure of human 21LT2-2 TCR bound to HLA-A*03:01 in complex with a mutant PIK3CA peptide
Descriptor: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
Authors:Ma, J, Baker, B.M.
Deposit date:2020-12-14
Release date:2022-03-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Nat Med, 28, 2022
6AM5
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BU of 6am5 by Molmil
Crystal structure of DMF5 TCR bound to HLA-A2 presenting synthetic peptide SMLGIGIVPV
Descriptor: Beta-2-microglobulin, DMF5 TCR alpha chain, DMF5 TCR beta chain, ...
Authors:Riley, T.P, Baker, B.M.
Deposit date:2017-08-09
Release date:2018-08-08
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:Crystal structure of DMF5 TCR bound to HLA-A2 presenting synthetic peptide SMLGIGIVPV
To Be Published
6AMU
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BU of 6amu by Molmil
Crystal structure of DMF5 TCR bound to HLA-A2 presenting synthetic peptide MMWDRGLGMM
Descriptor: Beta-2-microglobulin, DMF5 TCR alpha chain, DMF5 TCR beta chain, ...
Authors:Riley, T.P, Baker, B.M.
Deposit date:2017-08-11
Release date:2018-08-15
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Crystal structure of DMF5 TCR bound to HLA-A2 presenting synthetic peptide MMWDRGLGMM
To Be Published

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