1LP9

Xenoreactive complex AHIII 12.2 TCR bound to p1049/HLA-A2.1

Summary for 1LP9

• Entry DOI: 10.2210/pdb1lp9/pdb
• Descriptor: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, self-peptide P1049, ... (6 entities in total)
• Functional Keywords: immunoregulatory complex, class i mhc:tcr co-crystal, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01892; Secreted: P61769
• Total number of polymer chains: 10
• Total formula weight: 186660.05

Authors

Buslepp, J.,Wang, H.,Biddison, W.E.,Appella, E.,Collins, E.J. (deposition date: 2002-05-07, release date: 2003-11-11, Last modification date: 2023-09-20)

• Primary citation: Buslepp, J.,Wang, H.,Biddison, W.E.,Appella, E.,Collins, E.J.; A correlation between TCR Valpha docking on MHC and CD8 dependence: implications for T cell selection.; Immunity, 19:595-606, 2003; PubMed: 14563323; DOI: 10.1016/S1074-7613(03)00269-3

Experimental method

X-RAY DIFFRACTION (2 Å)