1GZP

CD1b in complex with GM2 ganglioside

Summary for 1GZP

Related1GZQ 1A1M 1A1N 1A1O 1A6Z 1A9B 1A9E 1AGB 1AGC 1AGD 1AGE 1AGF 1AKJ 1CE6 1DE4 1E27 1E28 1EFX 1EXU 1HHG 1HHH 1HHI 1HHJ 1HHK 1HLA 1HSA 1HSB 1I4F 1I7R 1I7T 1I7U 1IM3 1IM9 1JF1 1JHT 1JNJ 1QLF 1QQD 1TMC 2CLR 2HLA 3HLA
DescriptorT-CELL SURFACE GLYCOPROTEIN CD1B, B2-MICROGLOBULIN, N-[(1S,2S)-2-HYDROXY-1-({[(2R,3R,4S,5S,6R)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2-YL]OXY}METHYL)OCTADECYL]OCTADECANAMIDE, ... (6 entities in total)
Functional Keywordslipid, ganglioside, mhc, antigen presentation, glycoprotein
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains2
Total molecular weight46192.64
Authors
Gadola, S.D.,Zaccai, N.R.,Harlos, K.,Shepherd, D.,Ritter, G.,Schmidt, R.R.,Jones, E.Y.,Cerundolo, V. (deposition date: 2002-05-24, release date: 2002-07-31, Last modification date: 2018-02-28)
Primary citation
Gadola, S.D.,Zaccai, N.R.,Harlos, K.,Shepherd, D.,Castro-Palomino, J.C.,Ritter, G.,Schmidt, R.R.,Jones, E.Y.,Cerundolo, V.
Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains.
Nat. Immunol., 3:721-726, 2002
PubMed: 12118248 (PDB entries with the same primary citation)
DOI: 10.1038/ni821
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.26230.5%7.2%0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1gzp
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Molmil generated image of 1gzp
rotated about x axis by 90°
Molmil generated image of 1gzp
rotated about y axis by 90°