1JF1

Crystal structure of HLA-A2*0201 in complex with a decameric altered peptide ligand from the MART-1/Melan-A

Summary for 1JF1

• Entry DOI: 10.2210/pdb1jf1/pdb
• Related: 1JHT
• Descriptor: HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, beta-2-microglobulin, decameric peptide ligand from the MART-1/Melan-A, ... (5 entities in total)
• Functional Keywords: human, tumor immunity, melanoma antigen, mhc, vaccination, melanoma, class i, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01892; Secreted: P61769
• Total number of polymer chains: 3
• Total formula weight: 44784.14

Authors

Sliz, P.,Michielin, O.,Cerottini, J.C.,Luescher, I.,Romero, P.,Karplus, M.,Wiley, D.C. (deposition date: 2001-06-19, release date: 2001-09-14, Last modification date: 2011-07-13)

• Primary citation: Sliz, P.,Michielin, O.,Cerottini, J.C.,Luescher, I.,Romero, P.,Karplus, M.,Wiley, D.C.; Crystal structures of two closely related but antigenically distinct HLA-A2/melanocyte-melanoma tumor-antigen peptide complexes.; J.Immunol., 167:3276-3284, 2001; PubMed: 11544315

Experimental method

X-RAY DIFFRACTION (1.85 Å)