1EFX

STRUCTURE OF A COMPLEX BETWEEN THE HUMAN NATURAL KILLER CELL RECEPTOR KIR2DL2 AND A CLASS I MHC LIGAND HLA-CW3

Summary for 1EFX

Related2dl2
DescriptorHLA-CW3 (HEAVY CHAIN), BETA-2-MICROGLOBULIN, PEPTIDE FROM IMPORTIN ALPHA-2, ... (5 entities in total)
Functional Keywordsmhc, hla, class i, kir, nk cell receptor, immunoglobulin fold, receptor-mhc complex, immune system
Biological sourceHomo sapiens (human)
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Cellular locationSecreted P61769
Cytoplasm P52292
Cell membrane; Single-pass type I membrane protein P43627
Total number of polymer chains5
Total molecular weight89034.14
Authors
Boyington, J.C.,Motyka, S.A.,Schuck, P.,Brooks, A.G.,Sun, P.D. (deposition date: 2000-02-10, release date: 2000-06-14, Last modification date: 2011-07-13)
Primary citation
Boyington, J.C.,Motyka, S.A.,Schuck, P.,Brooks, A.G.,Sun, P.D.
Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand.
Nature, 405:537-543, 2000
PubMed: 10850706 (PDB entries with the same primary citation)
DOI: 10.1038/35014520
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers35 4.7% 6.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02