1AKJ

COMPLEX OF THE HUMAN MHC CLASS I GLYCOPROTEIN HLA-A2 AND THE T CELL CORECEPTOR CD8

Summary for 1AKJ

DescriptorMHC CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A*0201) (ALPHA CHAIN), BETA 2-MICROGLOBULIN, HIV REVERSE TRANSCRIPTASE EPITOPE, ... (5 entities in total)
Functional Keywordst-cell, glycoprotein, complex, immunology, complex (mhc i-peptide-cd8), complex (mhc i-peptide-cd8) complex, complex (mhc i/peptide/cd8)
Biological sourceHomo sapiens (human)
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Cellular locationMembrane; Single-pass type I membrane protein P01892
Secreted P61769
Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted P01732
Total number of polymer chains5
Total molecular weight71645.22
Authors
Tormo, J.,Stuart, D.I.,Jones, E.Y. (deposition date: 1997-05-21, release date: 1997-09-17, Last modification date: 2011-07-13)
Primary citation
Gao, G.F.,Tormo, J.,Gerth, U.C.,Wyer, J.R.,McMichael, A.J.,Stuart, D.I.,Bell, J.I.,Jones, E.Y.,Jakobsen, B.K.
Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2.
Nature, 387:630-634, 1997
PubMed: 9177355 (PDB entries with the same primary citation)
DOI: 10.1038/42523
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.65 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers6 0.5% 2.3% 2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-09-23