Crystal Structure Analysis of NY-ESO-1 epitope, SLLMWITQC, in complex with HLA-A2

Summary for 1S9W
Related1S9X 1S9Y
DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, NY-ESO-1 peptide, ... (5 entities in total)
Functional Keywordsimmune system
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted: P61769
Total number of polymer chains3
Total formula weight44794.85
Webb, A.I.,Dunstone, M.A.,Chen, W.,Aguilar, M.I.,Chen, Q.,Chang, L.,Kjer-Nielsen, L.,Beddoe, T.,McCluskey, J.,Rossjohn, J.,Purcell, A.W. (deposition date: 2004-02-05, release date: 2004-09-28, Last modification date: 2011-07-13)
Primary citationAguilar, M.I.,Beddoe, T.,Chang, L.,Chen, Q.,Chen, W.,Dunstone, M.A.,Jackson, H.,Kjer-Nielsen, L.,McCluskey, J.,Purcell, A.W.,Rossjohn, J.,Webb, A.I.
Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue
J.Biol.Chem., 279:23438-23446, 2004
PubMed: 15004033
DOI: 110.1074/jbc.M314066200
PDB entries with the same primary citation
Experimental method
Structure validation
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PDB entries from 2021-06-23