1SYV

HLA-B*4405 complexed to the dominant self ligand EEFGRAYGF

Summary for 1SYV
Related1SYS
DescriptorMHC class I antigen, Beta-2-microglobulin, major histocompatibility complex, class II, DR alpha, ... (4 entities in total)
Functional Keywordshla, mhc, class i, b44, immune system
Biological sourceHomo sapiens (human)
More
Cellular locationMembrane; Single-pass type I membrane protein: P30481
Secreted: P61769
Total number of polymer chains3
Total formula weight44997.87
Authors
Primary citationBeddoe, T.,Bharadwaj, M.,Bottomley, S.P.,Brooks, A.G.,Chang, L.,Crockford, T.,Ely, L.K.,Holdsworth, R.,Kjer-Nielsen, L.,Laham, N.,Macdonald, W.A.,McCluskey, J.,Mifsud, N.A.,Peh, C.A.,Purcell, A.W.,Rossjohn, J.,Tait, B.D.,Zernich, D.
Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion
J.Exp.Med., 200:13-24, 2004
PubMed: 15226359
DOI: 110.1084/jem.20031680
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation
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PDB entries from 2021-06-16