1ZT4

The crystal structure of human CD1d with and without alpha-Galactosylceramide

Summary for 1ZT4

DescriptorT-cell surface glycoprotein CD1d, Beta-2-microglobulin, N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE, ... (4 entities in total)
Functional Keywordshuman cd1d, cd1, mhc class i, empty binding groove, glycolipid, alpha-galactosylceramide, alpha-galcer, structural proteomics in europe, spine, structural genomics, immune system
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Single-pass type I membrane protein P15813
Secreted P61769
Total number of polymer chains4
Total molecular weight88254.66
Authors
Primary citation
Koch, M.,Stronge, V.S.,Shepherd, D.,Gadola, S.D.,Mathew, B.,Ritter, G.,Fersht, A.R.,Besra, G.S.,Schmidt, R.R.,Jones, E.Y.,Cerundolo, V.
The crystal structure of human CD1d with and without alpha-galactosylceramide
Nat.Immunol., 6:819-826, 2005
PubMed: 16007090 (PDB entries with the same primary citation)
DOI: 10.1038/ni1225
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.315395.1%8.7%2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1zt4
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Molmil generated image of 1zt4
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Molmil generated image of 1zt4
rotated about y axis by 90°