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2BGD

Structure-based design of Protein Tyrosine Phosphatase-1B Inhibitors

Summary for 2BGD
Entry DOI10.2210/pdb2bgd/pdb
Related1A5Y 1AAX 1BZC 1BZH 1BZJ 1C83 1C84 1C85 1C86 1C87 1C88 1ECV 1EEN 1EEO 1G1F 1G1G 1G1H 1G7F 1G7G 1GFY 1I57 1JF7 1KAK 1KAV 1L8G 1LQF 1NL9 1NNY 1NO6 1NWE 1NWL 1NZ7 1OEM 1OEO 1OES 1OET 1OEU 1OEV 1ONY 1ONZ 1PA1 1PH0 1PTT 1PTU 1PTV 1PTY 1PXH 1PYN 1Q1M 1Q6J 1Q6M 1Q6N 1Q6P 1Q6S 1Q6T 1QXK 1SUG 1T48 1T49 1T4J 1WAX 1XBO 2BGE
DescriptorPROTEIN-TYROSINE PHOSPHATASE NON-RECEPTOR TYPE 1, 5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE, CHLORIDE ION, ... (6 entities in total)
Functional Keywordsprotein tyrosine phosphatase, 1, 2, 5-thiadiazolidin-3-one-1, 1-dioxide template, hydrolase
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains1
Total formula weight37908.30
Authors
Primary citationBlack, E.,Breed, J.,Breeze, A.L.,Embrey, K.,Garcia, R.,Gero, T.W.,Godfrey, L.,Kenny, P.W.,Morley, A.D.,Minshull, C.A.,Pannifer, A.D.,Read, J.,Rees, A.,Russell, D.J.,Toader, D.,Tucker, J.
Structure-Based Design of Protein Tyrosine Phosphatase-1B Inhibitors
Bioorg.Med.Chem.Lett., 15:2503-, 2005
Cited by
PubMed: 15863305
DOI: 10.1016/J.BMCL.2005.03.068
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

217705

건을2024-03-27부터공개중

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