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8ZGT
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BU of 8zgt by Molmil
Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri state3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
Authors:Du, S, Deng, M.J, Xiao, J.Y.
Deposit date:2024-05-09
Release date:2024-07-10
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Structural insights into the high-affinity IgE receptor Fc epsilon RI complex.
Nature, 2024
8Y81
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BU of 8y81 by Molmil
Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
Authors:Du, S, Deng, M.J, Xiao, J.Y.
Deposit date:2024-02-05
Release date:2024-07-10
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Structural insights into the high-affinity IgE receptor Fc epsilon RI complex.
Nature, 2024
4H8W
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BU of 4h8w by Molmil
Crystal structure of non-neutralizing and ADCC-potent antibody N5-i5 in complex with HIV-1 clade A/E gp120 and sCD4.
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB HEAVY CHAIN OF ADCC AND NON-NEUTRALIZING ANTI-HIV-1 ANTIBODY N5-I5, ...
Authors:Tolbert, W.D, Acharya, P, Kwong, P.D, Pazgier, M.
Deposit date:2012-09-24
Release date:2014-04-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
5THR
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BU of 5thr by Molmil
Cryo-EM structure of a BG505 Env-sCD4-17b-8ANC195 complex
Descriptor: 17b Fab VH domain, 17b Fab VL domain, 8ANC195 G52K5 VH domain, ...
Authors:Wang, H, Bjorkman, P.J.
Deposit date:2016-09-30
Release date:2016-11-16
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop.
Proc.Natl.Acad.Sci.USA, 113, 2016
1GC1
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BU of 1gc1 by Molmil
HIV-1 GP120 CORE COMPLEXED WITH CD4 AND A NEUTRALIZING HUMAN ANTIBODY
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, CD4, ...
Authors:Kwong, P.D, Wyatt, R, Robinson, J, Sweet, R.W, Sodroski, J, Hendrickson, W.A.
Deposit date:1998-06-15
Release date:1998-07-08
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody.
Nature, 393, 1998
1G9M
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BU of 1g9m by Molmil
HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ...
Authors:Kwong, P.D, Wyatt, R, Majeed, S, Robinson, J, Sweet, R.W, Sodroski, J, Hendrickson, W.A.
Deposit date:2000-11-24
Release date:2000-12-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Structure Fold.Des., 8, 2000
5U1F
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BU of 5u1f by Molmil
Initial contact of HIV-1 Env with CD4: Cryo-EM structure of BG505 DS-SOSIP trimer in complex with CD4 and antibody PGT145
Descriptor: BG505 DS-SOSIP gp120, BG505 SOSIP gp41, PGT145 heavy chain, ...
Authors:Acharya, P, Kwong, P.D, Potter, C.S, Carragher, B.
Deposit date:2016-11-28
Release date:2017-02-22
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer.
Nat. Struct. Mol. Biol., 24, 2017
4PBW
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BU of 4pbw by Molmil
Crystal structure of chicken receptor protein tyrosine phosphatase sigma in complex with TrkC
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NT-3 growth factor receptor, Protein-tyrosine phosphatase CRYPalpha1 isoform
Authors:Coles, C.H, Mitakidis, N, Zhang, P, Elegheert, J, Lu, W, Stoker, A.W, Nakagawa, T, Craig, A.M, Jones, E.Y, Aricescu, A.R.
Deposit date:2014-04-14
Release date:2014-11-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis.
Nat Commun, 5, 2014
4P9H
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BU of 4p9h by Molmil
Crystal structure of 8ANC195 Fab in complex with gp120 of 93TH057 HIV-1 and soluble CD4 D1D2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2014-04-04
Release date:2014-05-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike.
Cell Rep, 7, 2014
1G9N
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BU of 1g9n by Molmil
HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ...
Authors:Kwong, P.D, Wyatt, R, Majeed, S, Robinson, J, Sweet, R.W, Sodroski, J, Hendrickson, W.A.
Deposit date:2000-11-25
Release date:2000-12-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Structure Fold.Des., 8, 2000
1EFX
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BU of 1efx by Molmil
STRUCTURE OF A COMPLEX BETWEEN THE HUMAN NATURAL KILLER CELL RECEPTOR KIR2DL2 AND A CLASS I MHC LIGAND HLA-CW3
Descriptor: BETA-2-MICROGLOBULIN, HLA-CW3 (HEAVY CHAIN), NATURAL KILLER CELL RECEPTOR KIR2DL2, ...
Authors:Boyington, J.C, Motyka, S.A, Schuck, P, Brooks, A.G, Sun, P.D.
Deposit date:2000-02-10
Release date:2000-06-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand.
Nature, 405, 2000
4IM8
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BU of 4im8 by Molmil
low resolution crystal structure of mouse RAGE
Descriptor: Advanced glycation end-products receptor
Authors:Xu, D, Young, J.H, Krahn, J.M, Song, D, Corbett, K.D, Chazin, W.J, Pedersen, L.C, Esko, J.D.
Deposit date:2013-01-02
Release date:2013-08-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.503 Å)
Cite:Stable RAGE-Heparan Sulfate Complexes Are Essential for Signal Transduction.
Acs Chem.Biol., 8, 2013
1ZVO
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BU of 1zvo by Molmil
Semi-extended solution structure of human myeloma immunoglobulin D determined by constrained X-ray scattering
Descriptor: Immunoglobulin delta heavy chain, myeloma immunoglobulin D lambda
Authors:Sun, Z, Almogren, A, Furtado, P.B, Chowdhury, B, Kerr, M.A, Perkins, S.J.
Deposit date:2005-06-02
Release date:2005-10-25
Last modified:2024-02-14
Method:SOLUTION SCATTERING
Cite:Semi-extended Solution Structure of Human Myeloma Immunoglobulin D Determined by Constrained X-ray Scattering.
J.Mol.Biol., 353, 2005
2QAD
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BU of 2qad by Molmil
Structure of tyrosine-sulfated 412d antibody complexed with HIV-1 YU2 gp120 and CD4
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Huang, C.-C, Tang, M, Robinson, J, Wyatt, R, Kwong, P.D.
Deposit date:2007-06-14
Release date:2007-09-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4
Science, 317, 2007
2QEJ
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BU of 2qej by Molmil
Crystal structure of a Staphylococcus aureus protein (SSL7) in complex with Fc of human IgA1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
Authors:Ramsland, P.A, Willoughby, N, Trist, H.M, Farrugia, W, Hogarth, P.M, Fraser, J.D, Wines, B.D.
Deposit date:2007-06-26
Release date:2007-09-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for evasion of IgA immunity by Staphylococcus aureus revealed in the complex of SSL7 with Fc of human IgA1
Proc.Natl.Acad.Sci.Usa, 104, 2007
7T0O
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BU of 7t0o by Molmil
cryoEM reconstruction of the HIV gp140 in complex with the extracellular domains of CD4 and the adnectin domain of Combinectin. The gp140 and CD4 coordinates from entry 6EDU were rigid body fitted to the EM map along withe the crystal structure of CD4+adnectin
Descriptor: Adnectin, BG505 SOSIP.664 gp140, T-cell surface glycoprotein CD4
Authors:Concha, N.O, William, S.P, Wenzel, D.L.
Deposit date:2021-11-30
Release date:2022-01-12
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment.
J.Mol.Biol., 434, 2021
7T0R
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BU of 7t0r by Molmil
Crystal structure of the anti-CD4 adnectin 6940_B01 as a complex with the extracellular domains of CD4 and ibalizumab fAb
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Adnectin 6940_B01, Ibalizumab Heavy Chain, ...
Authors:Williams, S.P, Concha, N.O, Wensel, D.L, Hong, X.
Deposit date:2021-11-30
Release date:2022-01-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment.
J.Mol.Biol., 434, 2021
7TTZ
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BU of 7ttz by Molmil
Heterodimeric IgA Fc in complex with Staphylococcus aureus protein SSL7
Descriptor: 1,2-ETHANEDIOL, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Boulanger, M.J, Verstraete, M, Heinkel, F, Escobar, E, Dixit, S, Von Kreudenstein, T.S.
Deposit date:2022-02-02
Release date:2023-02-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Engineering a pure and stable heterodimeric IgA for the development of multispecific therapeutics.
Mabs, 14, 2022
6L1Y
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BU of 6l1y by Molmil
structure of gp120/CD4 with a non-canonical surface
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, T-cell surface glycoprotein CD4, ...
Authors:Liu, X, Ning, W.
Deposit date:2019-10-01
Release date:2020-05-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.469 Å)
Cite:A non-canonical binding interface in the crystal structure of HIV-1 gp120 core in complex with CD4.
Sci Rep, 7, 2017
7TXD
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BU of 7txd by Molmil
Cryo-EM structure of BG505 SOSIP HIV-1 Env trimer in complex with CD4 receptor (D1D2) and broadly neutralizing darpin bnD.9
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Broadly neutralizing darpin bnd.9, ...
Authors:Cerutti, G, Gorman, J, Kwong, P.D, Shapiro, L.
Deposit date:2022-02-08
Release date:2023-04-12
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.
Nat.Struct.Mol.Biol., 30, 2023
6LX3
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BU of 6lx3 by Molmil
Cryo-EM structure of human secretory immunoglobulin A
Descriptor: Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor
Authors:Wang, Y, Wang, G, Li, Y, Xiao, J.
Deposit date:2020-02-10
Release date:2020-05-27
Last modified:2020-07-22
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin.
Cell Res., 30, 2020
7UVL
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BU of 7uvl by Molmil
IgA1 Protease with IgA1 substrate
Descriptor: Immunoglobulin alpha-1 heavy chain, Immunoglobulin alpha-1 heavy constant, Immunoglobulin alpha-1 light chain, ...
Authors:Eisenmesser, Z.E, Zheng, H.
Deposit date:2022-05-02
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:A substrate-induced gating mechanism is conserved among Gram-positive IgA1 metalloproteases.
Commun Biol, 5, 2022
6LXW
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BU of 6lxw by Molmil
Cryo-EM structure of human secretory immunoglobulin A in complex with the N-terminal domain of SpsA
Descriptor: Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor, ...
Authors:Wang, Y, Wang, G, Li, Y, Xiao, J.
Deposit date:2020-02-12
Release date:2020-05-27
Last modified:2020-07-22
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin.
Cell Res., 30, 2020
2X1X
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BU of 2x1x by Molmil
CRYSTAL STRUCTURE OF VEGF-C IN COMPLEX WITH DOMAINS 2 AND 3 OF VEGFR2 IN A TETRAGONAL CRYSTAL FORM
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MERCURY (II) ION, ...
Authors:Leppanen, V.-M, Prota, A.E, Jeltsch, M, Anisimov, A, Kalkkinen, N, Strandin, T, Lankinen, H, Goldman, A, Ballmer-Hofer, K, Alitalo, K.
Deposit date:2010-01-08
Release date:2010-02-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Determinants of Growth Factor Binding and Specificity by Vegf Receptor 2.
Proc.Natl.Acad.Sci.USA, 107, 2010
2X1W
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Crystal Structure of VEGF-C in Complex with Domains 2 and 3 of VEGFR2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CESIUM ION, ...
Authors:Leppanen, V.M, Prota, A.E, Jeltsch, M, Anisimov, A, Kalkkinen, N, Strandin, T, Lankinen, H, Goldman, A, Ballmer-Hofer, K, Alitalo, K.
Deposit date:2010-01-08
Release date:2010-03-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Determinants of Growth Factor Binding and Specificity by Vegf Receptor 2.
Proc.Natl.Acad.Sci.USA, 107, 2010

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