5THR

Cryo-EM structure of a BG505 Env-sCD4-17b-8ANC195 complex

Summary for 5THR

Entry DOI	10.2210/pdb5thr/pdb
EMDB information	8407
Descriptor	BG505 SOSIP gp41, BG505 SOSIP gp120, T-cell surface glycoprotein CD4, ... (9 entities in total)
Functional Keywords	cryo-em, hiv-1 env, cd4, viral protein
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	21
Total formula weight	577913.93
Authors	Wang, H.,Bjorkman, P.J. (deposition date: 2016-09-30, release date: 2016-11-16, Last modification date: 2020-07-29)
Primary citation	Wang, H.,Cohen, A.A.,Galimidi, R.P.,Gristick, H.B.,Jensen, G.J.,Bjorkman, P.J. Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop. Proc.Natl.Acad.Sci.USA, 113:E7151-E7158, 2016 Cited by PubMed: 27799557 DOI: 10.1073/pnas.1615939113 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (8.9 Å)

Structure validation