7TTZ
Heterodimeric IgA Fc in complex with Staphylococcus aureus protein SSL7
Summary for 7TTZ
| Entry DOI | 10.2210/pdb7ttz/pdb |
| Descriptor | IgA Fc, Superantigen-like protein SSL7, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
| Functional Keywords | iga, heterodimer, antibody fc, antibody engineering, immune system |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 96213.00 |
| Authors | Boulanger, M.J.,Verstraete, M.,Heinkel, F.,Escobar, E.,Dixit, S.,Von Kreudenstein, T.S. (deposition date: 2022-02-02, release date: 2023-02-01, Last modification date: 2023-10-25) |
| Primary citation | Heinkel, F.,Verstraete, M.M.,Cao, S.,Li, J.,Farber, P.,Stangle, E.,Silva-Moreno, B.,Peng, F.,Dixit, S.,Boulanger, M.J.,Spreter Von Kreudenstein, T.,Escobar-Cabrera, E. Engineering a pure and stable heterodimeric IgA for the development of multispecific therapeutics. Mabs, 14:2141637-2141637, 2022 Cited by PubMed: 36343329DOI: 10.1080/19420862.2022.2141637 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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