7TTZ

Heterodimeric IgA Fc in complex with Staphylococcus aureus protein SSL7

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	IgA Fc	polymer	220	23965.2	1	UniProt (Q6MZV6)	Homo sapiens (human)
2	B (B)	IgA Fc	polymer	220	23727.9	1	UniProt (Q6MZV6)	Homo sapiens (human)
3	C, D (C, D)	Superantigen-like protein SSL7	polymer	201	23050.0	2	UniProt (by SIFTS) (A0A9Y2YA69)	Staphylococcus aureus
4	E (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5	F, G, H, J, K... (A, B, C, D)	2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL	non-polymer		252.3	7	Chemie (1PG)
6	I, O (A, C)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
7	L, M, Q, R (B, D)	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
8	S, T, U, V (A, B, C, D)	water	water		18.0	162	Chemie (HOH)

Sequence modifications

A: 235 - 453 (UniProt: Q6MZV6)

PDB	External Database	Details
Arg 234	-	expression tag
Ser 311	Cys 318	engineered mutation
Thr 337	Asn 344	engineered mutation
Leu 338	Ile 345	engineered mutation
Ser 339	Thr 346	engineered mutation
Phe 412	Ala 419	engineered mutation
Tyr 414	Thr 421	engineered mutation

B: 235 - 453 (UniProt: Q6MZV6)

PDB	External Database	Details
Arg 234	-	expression tag
Ser 311	Cys 318	engineered mutation
Thr 337	Asn 344	engineered mutation
Leu 338	Ile 345	engineered mutation
Ser 339	Thr 346	engineered mutation
Val 396	Leu 403	engineered mutation
Thr 398	Trp 405	engineered mutation
Leu 416	Ile 423	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	93793.2
Non-Polymers*	Number of molecules	14
	Total formula weight	2419.8
All*	Total formula weight	96213.0

*Water molecules are not included.