4PBW

Crystal structure of chicken receptor protein tyrosine phosphatase sigma in complex with TrkC

Summary for 4PBW

• Entry DOI: 10.2210/pdb4pbw/pdb
• Related: 2YD4
• Descriptor: NT-3 growth factor receptor, Protein-tyrosine phosphatase CRYPalpha1 isoform, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: receptor protein tyrosine phosphatase (rptp), synapse cell signalling cell surface receptor, signaling protein
• Biological source: Gallus gallus (Chicken); More
• Total number of polymer chains: 6
• Total formula weight: 194051.01

Authors

Coles, C.H.,Mitakidis, N.,Zhang, P.,Elegheert, J.,Lu, W.,Stoker, A.W.,Nakagawa, T.,Craig, A.M.,Jones, E.Y.,Aricescu, A.R. (deposition date: 2014-04-14, release date: 2014-11-12, Last modification date: 2023-12-20)

• Primary citation: Coles, C.H.,Mitakidis, N.,Zhang, P.,Elegheert, J.,Lu, W.,Stoker, A.W.,Nakagawa, T.,Craig, A.M.,Jones, E.Y.,Aricescu, A.R.; Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis.; Nat Commun, 5:5209-5209, 2014; PubMed: 25385546; DOI: 10.1038/ncomms6209

Experimental method

X-RAY DIFFRACTION (3.05 Å)