6LXW

Cryo-EM structure of human secretory immunoglobulin A in complex with the N-terminal domain of SpsA

Summary for 6LXW

• Entry DOI: 10.2210/pdb6lxw/pdb
• EMDB information: 30008
• Descriptor: Interleukin-2,Immunoglobulin heavy constant alpha 1, Immunoglobulin J chain, Polymeric immunoglobulin receptor, ... (4 entities in total)
• Functional Keywords: immunoglobulin, dimer, transcytosis, secreted, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 7
• Total formula weight: 244625.98

Authors

Wang, Y.,Wang, G.,Li, Y.,Xiao, J. (deposition date: 2020-02-12, release date: 2020-05-27, Last modification date: 2020-07-22)

• Primary citation: Wang, Y.,Wang, G.,Li, Y.,Zhu, Q.,Shen, H.,Gao, N.,Xiao, J.; Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin.; Cell Res., 30:602-609, 2020; PubMed: 32398862; DOI: 10.1038/s41422-020-0336-3

Experimental method

ELECTRON MICROSCOPY (3.27 Å)