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Showing 1 - 50 of 55 items for (author: huang & xp)

EMDB-44865:
Local refinement of DRD2 bound to LSD in complex with a mini-GoA and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Kim K, Gumpper RH, Fay JF, Roth BL

EMDB-44866:
Global reconstruction of DRD2 bound to LSD in complex with a mini-GoA and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Kim K, Gumpper RH, Fay JF, Roth BL

EMDB-71718:
Locally-refined structure of alpha2a adrenergic receptor in complex with Go heterotrimer, scFv16, and N-(5-methylnaphthalen-1-yl)pyridin-4-amine (compound 4905)
Method: single particle / : Srinivasan K, Xu X, Mailhot O, Manglik A, Shoichet B

EMDB-71719:
Structure of alpha2a adrenergic receptor in complex with Go heterotrimer, scFv16, and N-(5-methylnaphthalen-1-yl)pyridin-4-amine (compound 4905)
Method: single particle / : Srinivasan K, Xu X, Mailhot O, Manglik A, Shoichet B

EMDB-45616:
CryoEM Structure of HCA2 DREADD Gi1 in complex with FCH-2296413 (Local Refinement)
Method: single particle / : Krumm BE, Kang HJ, Diberto JF, Kapolka NJ, Gumpper RH, Olsen RHJ, Huang XP, Zhang S, Fay JF, Roth BL

EMDB-45581:
CryoEM structure of delta opioid receptor bound to G proteins and a partial agonist
Method: single particle / : Fay JF, Che T

EMDB-45582:
CryoEM structure of delta opioid receptor bound to G proteins and a full bitopic agonist
Method: single particle / : Fay JF, Che T

EMDB-44199:
Biased agonist bound CB1-Gi structure
Method: single particle / : Rangari VA, O'Brien ES, Kobilka BK, Krishna Kumar K, Majumdar S

EMDB-44247:
Biased agonist bound CB1-Gi structure
Method: single particle / : Rangari VA, O'Brien ES, Kobilka BK, Krishna Kumar K, Majumdar S

EMDB-42538:
CryoEM Structure of HCA2-Gi1 in complex with MK-1903
Method: single particle / : Krumm BE, Kang HJ, Diberto JF, Kapolka NJ, Gumpper RH, Olsen RHJ, Huang XP, Zhang S, Fay JF, Roth BL

EMDB-42587:
CryoEM Structure of HCA2 DREADD Gi1 in complex with FCH-2296413
Method: single particle / : Krumm BE, Kang HJ, Diberto JF, Kapolka NJ, Gumpper RH, Olsen RHJ, Huang XP, Zhang S, Fay JF, Roth BL

EMDB-44548:
Human proton sensing receptor GPR65 in complex with miniGs - focused map of 7TM
Method: single particle / : Howard MK, Hoppe N, Huang XP, Macdonald CB, Mehrotra E, Rockefeller Grimes P, Zahm AM, Trinidad DD, English J, Coyote-Maestas W, Manglik A

EMDB-44549:
Human proton sensing receptor GPR65 in complex with miniGs
Method: single particle / : Howard MK, Hoppe N, Huang XP, Macdonald CB, Mehrotra E, Rockefeller Grimes P, Zahm AM, Trinidad DD, English J, Coyote-Maestas W, Manglik A

EMDB-44550:
Human proton sensing receptor GPR68 in complex with miniGs
Method: single particle / : Howard MK, Hoppe N, Huang XP, Macdonald CB, Mehrotra E, Rockefeller Grimes P, Zahm AM, Trinidad DD, English J, Coyote-Maestas W, Manglik A

EMDB-44560:
Human proton sensing receptor GPR68 in complex with miniGsq
Method: single particle / : Howard MK, Hoppe N, Huang XP, Macdonald CB, Mehrotra E, Rockefeller Grimes P, Zahm AM, Trinidad DD, English J, Coyote-Maestas W, Manglik A

EMDB-44561:
Human proton sensing receptor GPR68 in complex with miniGsq - focused map of 7TM
Method: single particle / : Howard MK, Hoppe N, Huang XP, Macdonald CB, Mehrotra E, Rockefeller Grimes P, Zahm AM, Trinidad DD, English J, Coyote-Maestas W, Manglik A

EMDB-44596:
Human proton sensing receptor GPR4 in complex with miniGs - focused map of 7TM
Method: single particle / : Howard MK, Hoppe N, Huang XP, Macdonald CB, Mehrotra E, Rockefeller Grimes P, Zahm AM, Trinidad DD, English J, Coyote-Maestas W, Manglik A

EMDB-44597:
Human proton sensing receptor GPR4 in complex with miniGs
Method: single particle / : Howard MK, Hoppe N, Huang XP, Macdonald CB, Mehrotra E, Rockefeller Grimes P, Zahm AM, Trinidad DD, English J, Coyote-Maestas W, Manglik A

EMDB-41766:
CryoEM structure of D2 dopamine receptor in complex with GoA KE mutant, scFv16, and dopamine
Method: single particle / : Krumm BE, Kapolka NJ, Fay JF, Roth BL

EMDB-41776:
CryoEM structure of D2 dopamine receptor in complex with GoA KE mutant and dopamine
Method: single particle / : Krumm BE, Kapolka NJ, Fay JF, Roth BL

EMDB-35683:
Dopamine Receptor D1R-Gs-Rotigotine complex
Method: single particle / : Xu P, Huang S, Zhuang Y, Mao C, Zhang Y, Wang Y, Li H, Jiang Y, Xu HE

EMDB-35686:
Dopamine Receptor D4R-Gi-Rotigotine complex
Method: single particle / : Xu P, Huang S, Zhuang Y, Mao C, Zhang Y, Wang Y, Li H, Jiang Y, Xu HE

EMDB-35684:
Dopamine Receptor D2R-Gi-Rotigotine complex
Method: single particle / : Xu P, Huang S, Zhuang Y, Mao C, Zhang Y, Wang Y, Li H, Jiang Y, Xu HE

EMDB-35685:
Dopamine Receptor D3R-Gi-Rotigotine complex
Method: single particle / : Xu P, Huang S, Zhuang Y, Mao C, Zhang Y, Wang Y, Li H, Jiang Y, Xu HE

EMDB-35687:
Dopamine Receptor D5R-Gs-Rotigotine complex
Method: single particle / : Xu P, Huang S, Zhuang Y, Mao C, Zhang Y, Wang Y, Li H, Jiang Y, Xu HE

EMDB-31479:
Cryo-EM structure of human angiotensin receptor AT1R in complex Gq proteins and Sar1-AngII
Method: single particle / : Zhang D, Xu L

EMDB-29301:
Neurotensin receptor allosterism revealed in complex with a biased allosteric modulator
Method: single particle / : Krumm BE, Diberto JF, Olsen RHJ, Kang H, Slocum ST, Zhang S, Strachan RT, Fay JF, Roth BL

EMDB-29302:
CryoEM structure of Go-coupled NTSR1 with a biased allosteric modulator
Method: single particle / : Krumm BE, DiBerto JF, Olsen RHJ, Kang H, Slocum ST, Zhang S, Strachan RT, Fay JF, Roth BL

EMDB-29303:
CryoEM structure of Go-coupled NTSR1
Method: single particle / : Krumm BE, DiBerto JF, Olsen RHJ, Kang H, Slocum ST, Zhang S, Strachan RT, Fay JF, Roth BL

EMDB-26160:
Structure of human serotonin transporter bound to small molecule '8090 in lipid nanodisc and NaCl
Method: single particle / : Singh I, Seth A

EMDB-27966:
CryoEM structure of miniGq-coupled hM3Dq in complex with DCZ
Method: single particle / : Zhang S, Fay JF, Roth BL

EMDB-27967:
CryoEM structure of miniGo-coupled hM4Di in complex with DCZ
Method: single particle / : Zhang S, Fay JF, Roth BL

EMDB-27968:
CryoEM structure of miniGq-coupled hM3Dq in complex with CNO
Method: single particle / : Zhang S, Fay JF, Roth BL

EMDB-27969:
CryoEM structure of miniGq-coupled hM3R in complex with Iperoxo
Method: single particle / : Zhang S, Fay JF, Roth BL

EMDB-27970:
CryoEM structure of miniGq-coupled hM3R in complex with iperoxo (local refinement)
Method: single particle / : Zhang S, Fay JF, Roth BL

EMDB-27752:
CryoEM structure of Gq-coupled MRGPRX1 with peptide agonist BAM8-22
Method: single particle / : Liu Y, Cao C, Fay JF, Roth BL

EMDB-27753:
CryoEM structure of Gq-coupled MRGPRX1 with peptide ligand BAM8-22 and positive allosteric modulator ML382
Method: single particle / : Liu Y, Cao C, Fay JF, Roth BL

EMDB-27754:
CryoEM structure of Gq-coupled MRGPRX1 with ligand Compound-16
Method: single particle / : Liu Y, Cao C, Fay JF, Roth BL

EMDB-32331:
Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a G protein biased agonist
Method: single particle / : Xu J, Fink EA, Shoichet BK, Du Y

EMDB-32342:
Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a biased agonist
Method: single particle / : Xu J, Fink EA

EMDB-24378:
5-HT2AR bound to a novel agonist in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Barros-Alvarez X, Kim K, Panova O

EMDB-24896:
CryoEM structure of Gq-coupled MRGPRX2 with peptide agonist Cortistatin-14
Method: single particle / : Cao C, Fay JF

EMDB-24897:
CryoEM structure of Gi-coupled MRGPRX2 with peptide agonist Cortistatin-14
Method: single particle / : Cao C, Fay JF

EMDB-24898:
CryoEM structure of Gq-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573
Method: single particle / : Cao C, Fay JF

EMDB-24899:
CryoEM structure of Gi-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573
Method: single particle / : Cao C, Fay JF

EMDB-24900:
CryoEM structure of Gq-coupled MRGPRX4 with small molecule agonist MS47134
Method: single particle / : Cao C, Fay JF

EMDB-30410:
Dopamine Receptor D3R-Gi-Pramipexole complex
Method: single particle / : Xu P, Huang S

EMDB-30411:
Dopamine Receptor D3R-Gi-PD128907 complex
Method: single particle / : Xu P, Huang S

EMDB-23390:
Allosteric modulator LY3154207 binding to SKF-81297-bound dopamine receptor 1 in complex with miniGs protein
Method: single particle / : Zhuang Y, Krumm B

EMDB-23391:
Allosteric modulator LY3154207 binding to dopamine-bound dopamine receptor 1 in complex with miniGs protein
Method: single particle / : Zhuang Y, Krumm B

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Nobel Prize for mechanically activated and temperature-gated ion channels

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