Author results

1SCZ
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IMPROVED STRUCTURAL MODEL FOR THE CATALYTIC DOMAIN OF E.COLI DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE
Descriptor:Dihydrolipoamide Succinyltransferase
Authors:Schormann, N., Symersky, J., Carson, M., Luo, M., Tsao, J., Johnson, D., Huang, W.-Y., Pruett, P., Lin, G., Li, S., Qiu, S., Arabashi, A., Bunzel, B., Luo, D., Nagy, L., Gray, R., Luan, C.-H., Zhang, Z., Lu, S., DeLucas, L.
Deposit date:2004-02-12
Release date:2004-03-02
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Improved structural model for the catalytic domain of E.coli dihydrolipoamide succinyltransferase
To be Published
1XHL
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CRYSTAL STRUCTURE OF PUTATIVE TROPINONE REDUCTASE-II FROM CAENORHABDITIS ELEGANS WITH COFACTOR AND SUBSTRATE
Descriptor:Short-chain dehydrogenase/reductase family member (5L265), putative Tropinone Reductase-II, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Schormann, N., Karpova, E., Zhou, J., Zhang, Y., Symersky, J., Bunzel, R., Huang, W.-Y., Arabshahi, A., Qiu, S., Luan, C.-H., Gray, R., Carson, M., Tsao, J., Luo, M., Johnson, D., Lu, S., Lin, G., Luo, D., Cao, Z., Li, S., McKInstry, A., Shang, Q., Chen, Y.-J., Bray, T., Nagy, L., DeLucas, L., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-09-20
Release date:2004-09-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of putative Tropinone Reductase-II from Caenorhabditis Elegans with Cofactor and Substrate
To be Published
1XKQ
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CRYSTAL STRUCTURE OF SHORT-CHAIN DEHYDROGENASE/REDUCTASE OF UNKNOWN FUNCTION FROM CAENORHABDITIS ELEGANS WITH COFACTOR
Descriptor:short-chain reductase family member (5D234), NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Schormann, N., Zhou, J., Karpova, E., Zhang, Y., Symersky, J., Bunzel, B., Huang, W.-Y., Arabshahi, A., Qiu, S., Luan, C.-H., Gray, R., Carson, M., Tsao, J., Luo, M., Johnson, D., Lu, S., Lin, G., Luo, D., Cao, Z., Li, S., McKinstry, A., Shang, Q., Chen, Y.-J., Bray, T., Nagy, L., DeLucas, L., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-09-29
Release date:2004-10-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Short-Chain Dehydrogenase/Reductase of unknown Function from Caenorhabditis Elegans with Cofactor
To be Published
1YIS
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STRUCTURAL GENOMICS OF CAENORHABDITIS ELEGANS: ADENYLOSUCCINATE LYASE
Descriptor:adenylosuccinate lyase, SULFATE ION
Authors:Symersky, J., Schormann, N., Lu, S., Zhang, Y., Karpova, E., Qiu, S., Huang, W., Cao, Z., Zhou, J., Luo, M., Arabshahi, A., McKinstry, A., Luan, C.-H., Luo, D., Johnson, D., An, J., Tsao, J., Delucas, L., Shang, Q., Gray, R., Li, S., Bray, T., Chen, Y.-J., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-01-12
Release date:2005-01-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural genomics of Caenorhabditis elegans: adenylosuccinate lyase
To be Published
2B34
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STRUCTURE OF MAR1 RIBONUCLEASE FROM CAENORHABDITIS ELEGANS
Descriptor:MAR1 Ribonuclease
Authors:Schormann, N., Karpova, E., Li, S., Symersky, J., Zhang, Y., Lu, S., Zhou, Q., Lin, G., Cao, Z., Luo, M., Qiu, S., Luan, C.-H., Luo, D., Huang, W., Shang, Q., McKinstry, A., An, J., Tsao, J., Carson, M., Stinnett, M., Chen, Y., Johnson, D., Gary, R., Arabshahi, A., Bunzel, R., Bray, T., DeLucas, L., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-09-19
Release date:2005-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.141 Å)
Cite:Structure of MAR1 Ribonuclease from Caenorhabditis elegans
To be Published
1TOV
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STRUCTURAL GENOMICS OF CAENORHABDITIS ELEGANS: CAP-GLY DOMAIN OF F53F4.3
Descriptor:Hypothetical protein F53F4.3 in chromosome V, SULFATE ION
Authors:Li, S., Finley, J., Liu, Z.J., Qiu, S.H., Luan, C.H., Carson, M., Tsao, J., Johnson, D., Lin, G., Zhao, J., Thomas, W., Nagy, L.A., Sha, B., Delucas, L.J., Richardson, D., Richardson, J., Wang, B.C., Luo, M., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-06-15
Release date:2004-07-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal Structure of the Cytoskeleton-Associated Protein Glycine-Rich (CAP-Gly) Domain
J.Biol.Chem., 277, 2002
1LPL
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STRUCTURAL GENOMICS OF CAENORHABDITIS ELEGANS: CAP-GLY DOMAIN OF F53F4.3
Descriptor:Hypothetical 25.4 kDa protein F53F4.3 in chromosome V
Authors:Li, S., Finley, J., Liu, Z.-J., Qiu, S.H., Luan, C.H., Carson, M., Tsao, J., Johnson, D., Lin, G., Zhao, J., Thomas, W., Nagy, L.A., Sha, B., DeLucas, L.J., Wang, B.-C., Luo, M., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2002-05-08
Release date:2002-05-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal Structure of the Cytoskeleton-associated Protein Glycine-rich (CAP-Gly) Domain
J.Biol.Chem., 277, 2002
1X9M
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T7 DNA POLYMERASE IN COMPLEX WITH AN N-2-ACETYLAMINOFLUORENE-ADDUCTED DNA
Descriptor:5'-D(*GP*GP*AP*GP*AP*GP*TP*GP*AP*TP*TP*GP*GP*TP*AP*GP*TP*GP*TP*GP*AP*(2DT))-3', 5'-D(*CP*CP*CP*(8FG)P*AP*TP*CP*AP*CP*AP*CP*TP*AP*CP*CP*AP*AP*TP*CP*AP*CP*TP*CP*TP*CP*C)-3', DNA polymerase, ...
Authors:Dutta, S., Li, Y., Johnson, D., Dzantiev, L., Richardson, C.C., Romano, L.J., Ellenberger, T.
Deposit date:2004-08-23
Release date:2004-10-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis.
Proc.Natl.Acad.Sci.USA, 101, 2004
1X9S
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T7 DNA POLYMERASE IN COMPLEX WITH A PRIMER/TEMPLATE DNA CONTAINING A DISORDERED N-2 AMINOFLUORENE ON THE TEMPLATE, CRYSTALLIZED WITH DIDEOXY-CTP AS THE INCOMING NUCLEOTIDE.
Descriptor:5'-D(*GP*GP*AP*GP*AP*GP*TP*GP*AP*TP*T*GP*GP*TP*AP*GP*TP*GP*TP*GP*AP*(2DT))-3', 5'-D(*CP*CP*CP*(AFG)P*AP*TP*CP*AP*CP*AP*CP*TP*AP*CP*CP*AP*AP*TP*CP*AP*CP*TP*CP*TP*CP*C)-3', DNA polymerase, ...
Authors:Dutta, S., Li, Y., Johnson, D., Dzantiev, L., Richardson, C.C., Romano, L.J., Ellenberger, T.
Deposit date:2004-08-24
Release date:2004-10-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1X9W
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T7 DNA POLYMERASE IN COMPLEX WITH A PRIMER/TEMPLATE DNA CONTAINING A DISORDERED N-2 AMINOFLUORENE ON THE TEMPLATE, CRYSTALLIZED WITH DIDEOXY-ATP AS THE INCOMING NUCLEOTIDE.
Descriptor:5'-D(*GP*GP*AP*GP*AP*GP*TP*GP*AP*TP*T*GP*GP*T*AP*GP*TP*GP*TP*GP*AP*(2DT))-3', 5'-D(*CP*CP*CP*(AFG)*AP*TP*CP*AP*CP*AP*CP*TP*AP*CP*CP*AP*AP*TP*CP*AP*CP*TP*CP*TP*CP*C)-3', DNA polymerase, ...
Authors:Dutta, S., Li, Y., Johnson, D., Dzantiev, L., Richardson, C.C., Romano, L.J., Ellenberger, T.
Deposit date:2004-08-24
Release date:2004-10-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis.
Proc.Natl.Acad.Sci.Usa, 101, 2004
3CDG
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HUMAN CD94/NKG2A IN COMPLEX WITH HLA-E
Descriptor:HLA class I histocompatibility antigen, alpha chain E, Beta-2-microglobulin, ...
Authors:Petrie, E.J., Clements, C.S., Lin, J., Sullivan, L.C., Johnson, D., Huyton, T., Heroux, A., Hoare, H.L., Beddoe, T., Reid, H.H., Wilce, M.C.J., Brooks, A.G., Rossjohn, J.
Deposit date:2008-02-26
Release date:2008-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence
J.Exp.Med., 205, 2008
1MO0
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STRUCTURAL GENOMICS OF CAENORHABDITIS ELEGANS: TRIOSE PHOSPHATE ISOMERASE
Descriptor:Triosephosphate isomerase, ACETATE ION, SULFATE ION
Authors:Symersky, J., Li, S., Finley, J., Liu, Z.-J., Qui, H., Luan, C.H., Carson, M., Tsao, J., Johnson, D., Lin, G., Zhao, J., Thomas, W., Nagy, L.A., Sha, B., DeLucas, L.J., Wang, B.-C., Luo, M., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2002-09-06
Release date:2002-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural genomics of Caenorhabditis elegans: triosephosphate isomerase
Proteins, 51, 2003
5MTF
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A MODULAR ROUTE TO NOVEL POTENT AND SELECTIVE INHIBITORS OF RHOMBOID INTRAMEMBRANE PROTEASES
Descriptor:Rhomboid protease GlpG, inhibitor, CHLORIDE ION, ...
Authors:Ticha, A., Stanchev, S., Vinothkumar, K.R., Mikles, D.C., Pachl, P., Svehlova, K., Nguyen, M.T.N., Verhelst, S.H.L., Johnson, D., Bachovchin, D., Lepsik, M., Majer, P., Strisovsky, K.
Deposit date:2017-01-09
Release date:2017-11-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:General and Modular Strategy for Designing Potent, Selective, and Pharmacologically Compliant Inhibitors of Rhomboid Proteases.
Cell Chem Biol, 24, 2017
1PZV
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CRYSTAL STRUCTURES OF TWO UBC (E2) ENZYMES OF THE UBIQUITIN-CONJUGATING SYSTEM IN CAENORHABDITIS ELEGANS
Descriptor:Probable ubiquitin-conjugating enzyme E2-19 kDa
Authors:Schormann, N., Lin, G., Li, S., Symersky, J., Qiu, S., Finley, J., Luo, D., Stanton, A., Carson, M., Luo, M., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2003-07-14
Release date:2003-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Crystal structures of two UBC (E2) enzymes of the ubiquitin-conjugating system in Caenorhabditis elegans
To be Published
1YO6
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CRYSTAL STRUCTURE OF THE PUTATIVE CARBONYL REDUCTASE SNIFFER OF CAENORHABDITIS ELEGANS
Descriptor:Putative Carbonyl Reductase Sniffer
Authors:Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-01-26
Release date:2005-02-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the putative Carbonyl Reductase Sniffer of Caenorhabditis elegans
To be Published
1YQ1
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STRUCTURAL GENOMICS OF CAENORHABDITIS ELEGANS: GLUTATHIONE S-TRANSFERASE
Descriptor:glutathione S-Transferase
Authors:Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-01-31
Release date:2005-02-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Genomics of Caenorhabditis Elegans: glutathione S-Transferase
To be Published
2GP4
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STRUCTURE OF [FES]CLUSTER-FREE APO FORM OF 6-PHOSPHOGLUCONATE DEHYDRATASE FROM SHEWANELLA ONEIDENSIS
Descriptor:6-phosphogluconate dehydratase
Authors:Schormann, N., Symersky, J., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2006-04-16
Release date:2006-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structure of [FeS]cluster-free Apo Form of 6-Phosphogluconate Dehydratase from Shewanella oneidensis
To be Published
1IJR
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CRYSTAL STRUCTURE OF LCK SH2 COMPLEXED WITH NONPEPTIDE PHOSPHOTYROSINE MIMETIC
Descriptor:PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK, (4-{2-ACETYLAMINO-2-[1-(3-CARBAMOYL-4-CYCLOHEXYLMETHOXY-PHENYL)-ETHYLCARBAMOYL}-ETHYL}-2-PHOSPHONO-PHENOXY)-ACETIC ACID
Authors:Kawahata, N.H., Yang, M.H., Luke, G.P., Shakespeare, W.C., Sundaramoorthi, R.
Deposit date:2001-04-27
Release date:2002-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A novel phosphotyrosine mimetic 4'-carboxymethyloxy-3'-phosphonophenylalanine (Cpp): exploitation in the design of nonpeptide inhibitors of pp60(Src) SH2 domain.
Bioorg.Med.Chem.Lett., 11, 2001
3BDW
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HUMAN CD94/NKG2A
Descriptor:Natural killer cells antigen CD94, NKG2-A/NKG2-B type II integral membrane protein
Authors:Sullivan, L.C., Clements, C.S.
Deposit date:2007-11-15
Release date:2008-01-01
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Heterodimeric Assembly of the CD94-NKG2 Receptor Family and Implications for Human Leukocyte Antigen-E Recognition
Immunity, 27, 2007
5EIG
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ENGINEERED HUMAN CYSTATHIONINE GAMMA LYASE (E59T, E339V) TO DEPLET CYSTEINE
Descriptor:Cystathionine gamma-lyase, SULFATE ION, CYSTEINE
Authors:Yan, W., Zhang, J.
Deposit date:2015-10-29
Release date:2016-11-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Systemic Depletion of Serum L-Cyst(e)ine with an Engineered Human Enzyme Mediates Potent Induction of ROS and Cancer Ablation
To Be Published