8PNM
Structure of human KCTD15 BTB domain mutant G88D crystal form 2
Summary for 8PNM
| Entry DOI | 10.2210/pdb8pnm/pdb |
| Descriptor | BTB/POZ domain-containing protein KCTD15 (2 entities in total) |
| Functional Keywords | oligomerisation, btb domain, gene regulation |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 12 |
| Total formula weight | 166976.53 |
| Authors | Cruz Walma, D.A.,Cros, J.,Bradshaw, W.,Richardson, W.,Chen, Z.,Chalk, R.,Wilkie, A.,Bullock, A.N. (deposition date: 2023-06-30, release date: 2024-03-20) |
| Primary citation | Miller, K.A.,Cruz Walma, D.A.,Pinkas, D.M.,Tooze, R.S.,Bufton, J.C.,Richardson, W.,Manning, C.E.,Hunt, A.E.,Cros, J.,Hartill, V.,Parker, M.J.,McGowan, S.J.,Twigg, S.R.F.,Chalk, R.,Staunton, D.,Johnson, D.,Wilkie, A.O.M.,Bullock, A.N. BTB domain mutations perturbing KCTD15 oligomerisation cause a distinctive frontonasal dysplasia syndrome. J Med Genet, 2024 Cited by PubMed: 38296633DOI: 10.1136/jmg-2023-109531 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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