1XHL

Crystal Structure of putative Tropinone Reductase-II from Caenorhabditis Elegans with Cofactor and Substrate

Summary for 1XHL

• Entry DOI: 10.2210/pdb1xhl/pdb
• Related: 1IPF 1OOE 1SPX
• Descriptor: Short-chain dehydrogenase/reductase family member (5L265), putative Tropinone Reductase-II, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 8-METHYL-8-AZABICYCLO[3,2,1]OCTAN-3-ONE, ... (4 entities in total)
• Functional Keywords: parallel beta-sheet of seven strands in the order 3214567, three alpha-helices on either side of beta-sheet, seventh alpha-helix on top of beta-sheet, structural genomics, protein structure initiative, scsg, psi, southeast collaboratory for structural genomics, secsg, oxidoreductase
• Biological source: Caenorhabditis elegans
• Total number of polymer chains: 2
• Total formula weight: 64876.83

Authors

Schormann, N.,Karpova, E.,Zhou, J.,Zhang, Y.,Symersky, J.,Bunzel, R.,Huang, W.-Y.,Arabshahi, A.,Qiu, S.,Luan, C.-H.,Gray, R.,Carson, M.,Tsao, J.,Luo, M.,Johnson, D.,Lu, S.,Lin, G.,Luo, D.,Cao, Z.,Li, S.,McKInstry, A.,Shang, Q.,Chen, Y.-J.,Bray, T.,Nagy, L.,DeLucas, L.,Southeast Collaboratory for Structural Genomics (SECSG) (deposition date: 2004-09-20, release date: 2004-09-28, Last modification date: 2023-08-23)

• Primary citation: Schormann, N.,Karpova, E.,Zhou, J.,Zhang, Y.,Symersky, J.,Bunzel, R.,Huang, W.-Y.,Arabshahi, A.,Qiu, S.,Luan, C.-H.,Gray, R.,Carson, M.,Tsao, J.,Luo, M.,Johnson, D.,Lu, S.,Lin, G.,Luo, D.,Cao, Z.,Li, S.,McKInstry, A.,Shang, Q.,Chen, Y.-J.,Bray, T.,Nagy, L.,DeLucas, L.; Crystal Structure of putative Tropinone Reductase-II from Caenorhabditis Elegans with Cofactor and Substrate; To be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)