1XHL

Crystal Structure of putative Tropinone Reductase-II from Caenorhabditis Elegans with Cofactor and Substrate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Short-chain dehydrogenase/reductase family member (5L265), putative Tropinone Reductase-II	polymer	297	31553.8	2	UniProt (Q19774) Pfam (PF13561)	Caenorhabditis elegans
2	C, E (A, B)	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	2	Chemie (NDP)
3	D, F (A, B)	8-METHYL-8-AZABICYCLO[3,2,1]OCTAN-3-ONE	non-polymer		139.2	2	Chemie (TNE)
4	G, H (A, B)	water	water		18.0	234	Chemie (HOH)

Sequence modifications

A, B: 1 - 277 (UniProt: Q19774)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	63107.6
Non-Polymers*	Number of molecules	4
	Total formula weight	1769.2
All*	Total formula weight	64876.8

*Water molecules are not included.