3CDG
Human CD94/NKG2A in complex with HLA-E
Summary for 3CDG
Entry DOI | 10.2210/pdb3cdg/pdb |
Descriptor | HLA class I histocompatibility antigen, alpha chain E, Beta-2-microglobulin, Natural killer cells antigen CD94, ... (5 entities in total) |
Functional Keywords | nk cell receptor, immunity, c-type lectin, mhc, glycoprotein, immune response, membrane, mhc i, polymorphism, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, alternative splicing, signal-anchor, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P13747 P17693 Secreted: P61769 Membrane; Single-pass type II membrane protein: Q13241 P26715 |
Total number of polymer chains | 10 |
Total formula weight | 145509.85 |
Authors | Petrie, E.J.,Clements, C.S.,Lin, J.,Sullivan, L.C.,Johnson, D.,Huyton, T.,Heroux, A.,Hoare, H.L.,Beddoe, T.,Reid, H.H.,Wilce, M.C.J.,Brooks, A.G.,Rossjohn, J. (deposition date: 2008-02-26, release date: 2008-04-22, Last modification date: 2023-11-01) |
Primary citation | Petrie, E.J.,Clements, C.S.,Lin, J.,Sullivan, L.C.,Johnson, D.,Huyton, T.,Heroux, A.,Hoare, H.L.,Beddoe, T.,Reid, H.H.,Wilce, M.C.J.,Brooks, A.G.,Rossjohn, J. CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence J.Exp.Med., 205:725-735, 2008 Cited by PubMed: 18332182DOI: 10.1084/jem.20072525 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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