5ZKP | | CRYSTAL STRUCTURE OF THE HUMAN PLATELET-ACTIVATING FACTOR RECEPTOR IN COMPLEX WITH SR 27417 | | Descriptor: | Platelet-activating factor receptor,Flavodoxin,Platelet-activating factor receptor, N1,N1-dimethyl-N2-[(pyridin-3-yl)methyl]-N2-{4-[2,4,6-tri(propan-2-yl)phenyl]-1,3-thiazol-2-yl}ethane-1,2-diamine, FLAVIN MONONUCLEOTIDE | | Authors: | Cao, C., Zhao, Q., Zhang, X.C., Wu, B. | | Deposit date: | 2018-03-25 | | Release date: | 2018-06-20 | | Method: | X-RAY DIFFRACTION (2.81 Å) | | Cite: | Structural basis for signal recognition and transduction by platelet-activating-factor receptor.
Nat. Struct. Mol. Biol., 25, 2018
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5ZKQ | | CRYSTAL STRUCTURE OF THE HUMAN PLATELET-ACTIVATING FACTOR RECEPTOR IN COMPLEX WITH ABT-491 | | Descriptor: | Platelet-activating factor receptor,Endolysin,Endolysin,Platelet-activating factor receptor, 4-ethynyl-3-{3-fluoro-4-[(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)methyl]benzene-1-carbonyl}-N,N-dimethyl-1H-indole-1-carboxamide, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... | | Authors: | Cao, C., Zhao, Q., Zhang, X.C., Wu, B. | | Deposit date: | 2018-03-25 | | Release date: | 2018-06-20 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural basis for signal recognition and transduction by platelet-activating-factor receptor.
Nat. Struct. Mol. Biol., 25, 2018
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1P7M | | SOLUTION STRUCTURE AND BASE PERTURBATION STUDIES REVEAL A NOVEL MODE OF ALKYLATED BASE RECOGNITION BY 3-METHYLADENINE DNA GLYCOSYLASE I | | Descriptor: | DNA-3-methyladenine glycosylase I, ZINC ION, 3-METHYL-3H-PURIN-6-YLAMINE | | Authors: | Cao, C., Kwon, K., Jiang, Y.L., Drohat, A.C., Stivers, J.T. | | Deposit date: | 2003-05-02 | | Release date: | 2003-11-25 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure and base perturbation studies reveal a novel mode of alkylated base recognition by 3-methyladenine DNA glycosylase I
J.Biol.Chem., 278, 2003
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6K3J | | SOLUTION STRUCTURE OF APOBEC3G-CD2 WITH SSDNA, PRODUCT A | | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, DNA (5'-D(*AP*TP*TP*CP*UP*(IUR)P*AP*AP*TP*T)-3'), ZINC ION | | Authors: | Cao, C., Yan, X., Lan, W., Wang, C. | | Deposit date: | 2019-05-19 | | Release date: | 2019-06-12 | | Last modified: | 2019-07-17 | | Method: | SOLUTION NMR | | Cite: | Structural Investigations on the Interactions between Cytidine Deaminase Human APOBEC3G and DNA.
Chem Asian J, 14, 2019
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6K3K | | SOLUTION STRUCTURE OF APOBEC3G-CD2 WITH SSDNA, PRODUCT B | | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, DNA/RNA (5'-D(*AP*TP*TP*CP*UP*(ICY)P*AP*AP*TP*T)-3'), ZINC ION | | Authors: | Cao, C., Yan, X., Lan, W., Wang, C. | | Deposit date: | 2019-05-19 | | Release date: | 2019-06-12 | | Last modified: | 2019-07-17 | | Method: | SOLUTION NMR | | Cite: | Structural Investigations on the Interactions between Cytidine Deaminase Human APOBEC3G and DNA.
Chem Asian J, 14, 2019
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1J0Q | | SOLUTION STRUCTURE OF OXIDIZED BOVINE MICROSOMAL CYTOCHROME B5 MUTANT V61H | | Descriptor: | cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Wu, H., Huang, Z., Cao, C., Zhang, Q., Wang, Y.-H., Ma, J.-B., Xue, L.-L. | | Deposit date: | 2002-11-20 | | Release date: | 2003-08-12 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | The solution structure of the oxidized bovine microsomal cytochrome b5 mutant V61H
Biochem.Biophys.Res.Commun., 307, 2003
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6JWD | | STRUCTURE OF RET G-QUADRUPLEX IN COMPLEX WITH BERBERINE | | Descriptor: | DNA (5'-D(*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3'), BERBERINE | | Authors: | Wang, F., Wang, C., Liu, Y., Lan, W.X., Li, Y.M., Wang, R.X., Cao, C. | | Deposit date: | 2019-04-19 | | Release date: | 2020-04-22 | | Method: | SOLUTION NMR | | Cite: | Colchicine selective interaction with oncogene RET G-quadruplex revealed by NMR.
Chem.Commun.(Camb.), 56, 2020
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6JWE | | STRUCTURE OF RET G-QUADRUPLEX IN COMPLEX WITH COLCHICINE | | Descriptor: | DNA (5'-D(*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3'), N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide | | Authors: | Wang, F., Wang, C., Liu, Y., Lan, W.X., Li, Y.M., Wang, R.X., Cao, C. | | Deposit date: | 2019-04-20 | | Release date: | 2020-02-26 | | Last modified: | 2020-03-04 | | Method: | SOLUTION NMR | | Cite: | Colchicine selective interaction with oncogene RET G-quadruplex revealed by NMR.
Chem.Commun.(Camb.), 56, 2020
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2LGG | | STRUCTURE OF PHD DOMAIN OF UHRF1 IN COMPLEX WITH H3 PEPTIDE | | Descriptor: | E3 ubiquitin-protein ligase UHRF1, histone H3 peptide, ZINC ION | | Authors: | Wang, C., Shen, J., Yang, Z., Chen, P., Zhao, B., Hu, W., Lan, W., Tong, X., Wu, H., Li, G., Cao, C. | | Deposit date: | 2011-07-26 | | Release date: | 2011-09-28 | | Method: | SOLUTION NMR | | Cite: | Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger.
Cell Res., 21, 2011
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2LGK | | NMR STRUCTURE OF UHRF1 PHD DOMAINS IN A COMPLEX WITH HISTONE H3 PEPTIDE | | Descriptor: | E3 ubiquitin-protein ligase UHRF1, histone H3 peptide, ZINC ION | | Authors: | Wang, C., Shen, J., Yang, Z., Chen, P., Zhao, B., Hu, W., Lan, W., Tong, X., Wu, H., Li, G., Cao, C. | | Deposit date: | 2011-07-28 | | Release date: | 2011-09-28 | | Method: | SOLUTION NMR | | Cite: | Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger.
Cell Res., 21, 2011
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2LGL | | NMR STRUCTURE OF THE UHRF1 PHD DOMAIN | | Descriptor: | E3 ubiquitin-protein ligase UHRF1, ZINC ION | | Authors: | Wang, C., Shen, J., Yang, Z., Chen, P., Zhao, B., Hu, W., Lan, W., Tong, X., Wu, H., Li, G., Cao, C. | | Deposit date: | 2011-07-28 | | Release date: | 2011-09-28 | | Method: | SOLUTION NMR | | Cite: | Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger.
Cell Res., 21, 2011
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2LUH | | NMR STRUCTURE OF THE VTA1-VPS60 COMPLEX | | Descriptor: | Vacuolar protein sorting-associated protein VTA1, Vacuolar protein-sorting-associated protein 60 | | Authors: | Yang, Z., Vild, C., Ju, J., Zhang, X., Liu, J., Shen, J., Zhao, B., Lan, W., Gong, F., Liu, M., Cao, C., Xu, Z. | | Deposit date: | 2012-06-13 | | Release date: | 2012-11-07 | | Last modified: | 2013-01-09 | | Method: | SOLUTION NMR | | Cite: | Structural Basis of Molecular Recognition between ESCRT-III-like Protein Vps60 and AAA-ATPase Regulator Vta1 in the Multivesicular Body Pathway.
J.Biol.Chem., 287, 2012
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2MY5 | | SOLUTION STRUCTURE OF KSTB-PCP IN KOSINOSTATIN BIOSYNTHESIS | | Descriptor: | Peptidyl carrier protein, N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-(2-sulfanylethyl)-beta-alaninamide | | Authors: | Zhao, B., Lan, W., Wang, C., Tang, G., Cao, C. | | Deposit date: | 2015-01-20 | | Release date: | 2016-01-20 | | Method: | SOLUTION NMR | | Cite: | 1H and 15N Assigned Chemical Shifts for KstB-PCP
To be Published
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2MY6 | |
4ROV | | THE CRYSTAL STRUCTURE OF NOVEL APOBEC3G CD2 HEAD-TO-TAIL DIMER SUGGESTS THE BINDING MODE OF FULL-LENGTH APOBEC3G TO HIV-1 SSDNA | | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION | | Authors: | Lu, X., Zhang, T., Xu, Z., Liu, S., Zhao, B., Lan, W., Wang, C., Ding, J., Cao, C. | | Deposit date: | 2014-10-29 | | Release date: | 2014-12-31 | | Last modified: | 2016-02-17 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA
J.Biol.Chem., 290, 2015
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4ROW | | THE CRYSTAL STRUCTURE OF NOVEL APOBEC3G CD2 HEAD-TO-TAIL DIMER SUGGESTS THE BINDING MODE OF FULL-LENGTH APOBEC3G TO HIV-1 SSDNA | | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION | | Authors: | Lu, X., Zhang, T., Xu, Z., Liu, S., Zhao, B., Lan, W., Wang, C., Ding, J., Cao, C. | | Deposit date: | 2014-10-29 | | Release date: | 2014-12-31 | | Last modified: | 2016-02-17 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA
J.Biol.Chem., 290, 2015
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4ZA1 | | CRYSTAL STRUCTURE OF NOSA INVOLVED IN NOSIHEPTIDE BIOSYNTHESIS | | Descriptor: | NosA, 2,3-DIHYDROXY-1,4-DITHIOBUTANE | | Authors: | Liu, S., Guo, H., Zhang, T., Han, L., Yao, P., Zhang, Y., Rong, N., Yu, Y., Lan, W., Wang, C., Ding, J., Wang, R., Liu, W., Cao, C. | | Deposit date: | 2015-04-13 | | Release date: | 2015-08-19 | | Last modified: | 2015-09-02 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure-based Mechanistic Insights into Terminal Amide Synthase in Nosiheptide-Represented Thiopeptides Biosynthesis
Sci Rep, 5, 2015
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5IAY | | NMR STRUCTURE OF UHRF1 TANDEM TUDOR DOMAINS IN A COMPLEX WITH SPACER PEPTIDE | | Descriptor: | E3 ubiquitin-protein ligase UHRF1, Spacer | | Authors: | Fang, J., Cheng, J., Wang, J., Zhang, Q., Liu, M., Gong, R., Wang, P., Zhang, X., Feng, Y., Lan, W., Gong, Z., Tang, C., Wong, J., Yang, H., Cao, C., Xu, Y. | | Deposit date: | 2016-02-22 | | Release date: | 2016-04-20 | | Method: | SOLUTION NMR | | Cite: | Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition
Nat Commun, 7, 2016
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5WTU | |
5Z9X | | ARABIDOPSIS SMALL RNA DEGRADING NUCLEASE 1 IN COMPLEX WITH AN RNA SUBSTRATE | | Descriptor: | Small RNA degrading nuclease 1, RNA (5'-R(P*GP*CP*CP*CP*AP*UP*UP*AP*G)-3'), SULFATE ION, ... | | Authors: | Chen, J., Liu, L., You, C., Gu, J., Ruan, W., Zhang, L., Gan, J., Cao, C., Huang, Y., Chen, X., Ma, J. | | Deposit date: | 2018-02-05 | | Release date: | 2018-06-27 | | Last modified: | 2018-10-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1.
Nat Commun, 9, 2018
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5Z9Z | | THE C-TERMINAL RRM DOMAIN OF ARABIDOPSIS SMALL RNA DEGRADING NUCLEASE 1 (E329A/E330A/E332A) | | Descriptor: | Small RNA degrading nuclease 1, CITRATE ANION | | Authors: | Chen, J., Liu, L., You, C., Gu, J., Ruan, W., Zhang, L., Cao, C., Gan, J., Huang, Y., Chen, X., Ma, J. | | Deposit date: | 2018-02-05 | | Release date: | 2018-06-27 | | Last modified: | 2018-10-03 | | Method: | X-RAY DIFFRACTION (2.049 Å) | | Cite: | Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1.
Nat Commun, 9, 2018
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5ID3 | | SOLUTION STRUCTURE OF THE PORE-FORMING REGION OF C. ELEGANS MITOCHONDRIAL CALCIUM UNIPORTER (MCU) | | Descriptor: | Mitochondrial Calcium Uniporter | | Authors: | Oxenoid, K., Dong, Y., Cao, C., Cui, T., Sancak, Y., Markhard, A.L., Grabarek, Z., Kong, L., Liu, Z., Ouyang, B., Cong, Y., Mootha, V.K., Chou, J.J., Membrane Protein Structures by Solution NMR (MPSbyNMR) | | Deposit date: | 2016-02-23 | | Release date: | 2016-05-04 | | Last modified: | 2019-12-25 | | Method: | SOLUTION NMR | | Cite: | Architecture of the mitochondrial calcium uniporter.
Nature, 533, 2016
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5J3F | | NMR SOLUTION STRUCTURE OF [RP, RP]-PT DSDNA | | Descriptor: | DNA (5'-D(*CP*GP*(RSG)P*CP*CP*GP*CP*CP*GP*A)-3'), DNA (5'-D(*TP*CP*GP*GP*CP*GP*(RSG)P*CP*CP*G)-3') | | Authors: | Lan, W., Hu, Z., Cao, C. | | Deposit date: | 2016-03-30 | | Release date: | 2016-11-16 | | Method: | SOLUTION NMR | | Cite: | Structural investigation into physiological DNA phosphorothioate modification
Sci Rep, 6, 2016
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5J3G | |
5J3I | | NMR SOLUTION STRUCTURE OF [SP, SP]-PT DSDNA | | Descriptor: | DNA (5'-D(*CP*GP*(SSG)P*CP*CP*GP*CP*CP*GP*A)-3'), DNA (5'-D(*TP*CP*GP*GP*CP*GP*(SSG)P*CP*CP*G)-3') | | Authors: | Lan, W., Hu, Z., Cao, C. | | Deposit date: | 2016-03-30 | | Release date: | 2016-11-16 | | Method: | SOLUTION NMR | | Cite: | Structural investigation into physiological DNA phosphorothioate modification
Sci Rep, 6, 2016
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