5ZKP
Crystal structure of the human platelet-activating factor receptor in complex with SR 27417
Summary for 5ZKP
Entry DOI | 10.2210/pdb5zkp/pdb |
Descriptor | Platelet-activating factor receptor,Flavodoxin,Platelet-activating factor receptor, N1,N1-dimethyl-N2-[(pyridin-3-yl)methyl]-N2-{4-[2,4,6-tri(propan-2-yl)phenyl]-1,3-thiazol-2-yl}ethane-1,2-diamine, FLAVIN MONONUCLEOTIDE (3 entities in total) |
Functional Keywords | g protein-coupled receptor, platelet-activating factor receptor, complex, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 53351.53 |
Authors | Cao, C.,Zhao, Q.,Zhang, X.C.,Wu, B. (deposition date: 2018-03-25, release date: 2018-06-20, Last modification date: 2023-11-22) |
Primary citation | Cao, C.,Tan, Q.,Xu, C.,He, L.,Yang, L.,Zhou, Y.,Zhou, Y.,Qiao, A.,Lu, M.,Yi, C.,Han, G.W.,Wang, X.,Li, X.,Yang, H.,Rao, Z.,Jiang, H.,Zhao, Y.,Liu, J.,Stevens, R.C.,Zhao, Q.,Zhang, X.C.,Wu, B. Structural basis for signal recognition and transduction by platelet-activating-factor receptor. Nat. Struct. Mol. Biol., 25:488-495, 2018 Cited by PubMed: 29808000DOI: 10.1038/s41594-018-0068-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.81 Å) |
Structure validation
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