7XFV

Dimeric G-quadruplex DNA Formed in the Proximal Promoter of VEGFR-2

Summary for 7XFV

• Entry DOI: 10.2210/pdb7xfv/pdb
• Descriptor: DNA (5'-D(*AP*TP*GP*AP*GP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3') (1 entity in total)
• Functional Keywords: angiogenesis, vegfr-2, g-quadruplex, dna
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 8883.75

Authors

Zhang, Y.,Lan, W.,Wang, C.,Cao, C. (deposition date: 2022-04-02, release date: 2023-03-15, Last modification date: 2023-03-22)

• Primary citation: Zhang, Y.,Lan, W.,Wang, C.,Xue, H.,Cao, C.; Dimeric G-quadruplex DNA Structure in the Proximal Promoter of VEGFR-2 Reveals a New Drug Target to Inhibit Tumor Angiogenesis.; Chin.J.Chem., 40:2179-2187, 2023; DOI: 10.1002/cjoc.202200260

Experimental method

SOLUTION NMR