7D3W

Non-specific and specific interactions work cooperatively to promote cytidine deamination catalyzed by APOBEC3A

Summary for 7D3W

• Entry DOI: 10.2210/pdb7d3w/pdb
• Descriptor: DNA dC->dU-editing enzyme APOBEC-3A, DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*TP*T)-3'), ZINC ION (3 entities in total)
• Functional Keywords: dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 26124.31

Authors

Cao, C.,Liu, Y.,Lan, W. (deposition date: 2020-09-21, release date: 2021-10-06, Last modification date: 2023-06-14)

• Primary citation: Liu, Y.,Lan, W.,Wang, C.,Cao, C.; Two different kinds of interaction modes of deaminase APOBEC3A with single-stranded DNA in solution detected by nuclear magnetic resonance.; Protein Sci., 31:443-453, 2022; PubMed: 34792260; DOI: 10.1002/pro.4242

Experimental method

SOLUTION NMR