PDB: 125 resultsInfo pagesStatus searchChemie searchBIRD

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2LOH	Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environment Descriptor: P3(42) Authors: Nadezhdin, K, Bocharov, E, Bocharova, O, Arseniev, A. Deposit date: 2012-01-24 Release date: 2012-05-23 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environment. Febs Lett., 586, 2012
2LP1	The solution NMR structure of the transmembrane C-terminal domain of the amyloid precursor protein (C99) Descriptor: C99 Authors: Barrett, P.J, Song, Y, Van Horn, W.D, Hustedt, E.J, Schafer, J.M, Hadziselimovic, A, Beel, A.J, Sanders, C.R. Deposit date: 2012-01-30 Release date: 2012-06-06 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: The amyloid precursor protein has a flexible transmembrane domain and binds cholesterol. Science, 336, 2012
2LZ3	Solution NMR structure of transmembrane domain of amyloid precursor protein WT Descriptor: Amyloid beta A4 protein Authors: Chen, W, Wang, C. Deposit date: 2012-09-23 Release date: 2013-10-02 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Familial Alzheimer's mutations within APPTM increase A beta 42 production by enhancing accessibility of epsilon-cleavage site. Nat Commun, 5, 2014
2LZ4	Solution NMR structure of transmembrane domain of amyloid precursor protein V44M Descriptor: Amyloid beta A4 protein Authors: Chen, W, Wang, C. Deposit date: 2012-09-23 Release date: 2013-10-02 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Familial Alzheimer's mutations within APPTM increase A beta 42 production by enhancing accessibility of epsilon-cleavage site. Nat Commun, 5, 2014
4HIX	Crystal structure of a humanised 3D6 Fab bound to amyloid beta peptide Descriptor: Beta-amyloid protein 40, Humanized 3D6 Fab heavy chain, Humanized 3D6 Fab light chain Authors: Miles, L.A, Crespi, G.A.N, Parker, M.W. Deposit date: 2012-10-12 Release date: 2013-03-13 Last modified: 2014-03-19 Method: X-RAY DIFFRACTION (2.204 Å) Cite: Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation. Sci Rep, 3, 2013
2M4J	40-residue beta-amyloid fibril derived from Alzheimer's disease brain Descriptor: Amyloid beta A4 protein Authors: Lu, J, Qiang, W, Meredith, S.C, Yau, W, Schweiters, C.D, Tycko, R. Deposit date: 2013-02-05 Release date: 2013-09-25 Last modified: 2024-05-15 Method: SOLID-STATE NMR Cite: Molecular Structure of beta-Amyloid Fibrils in Alzheimer's Disease Brain Tissue. Cell(Cambridge,Mass.), 154, 2013
2M9R	3D NMR structure of a complex between the amyloid beta peptide (1-40) and the polyphenol epsilon-viniferin glucoside Descriptor: (2S,3S)-3-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-6-yl beta-D-glucopyranoside, Amyloid beta A4 protein Authors: Monti, J, Richard, T. Deposit date: 2013-06-19 Release date: 2013-09-11 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: 3D NMR structure of a complex between the amyloid beta peptide (1-40) and the polyphenol epsilon-viniferin glucoside: Implications in Alzheimer's disease. Biochim.Biophys.Acta, 1830, 2013
2M9S	3D NMR structure of a complex between the amyloid beta peptide (1-40) and the polyphenol epsilon-viniferin glucoside Descriptor: (2S,3S)-3-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-6-yl beta-D-glucopyranoside, Amyloid beta A4 protein Authors: Monti, J, Richard, T. Deposit date: 2013-06-19 Release date: 2013-09-11 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: 3D NMR structure of a complex between the amyloid beta peptide (1-40) and the polyphenol epsilon-viniferin glucoside: Implications in Alzheimer's disease. Biochim.Biophys.Acta, 1830, 2013
4M1C	Crystal Structure Analysis of Fab-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Amyloid-Beta (1-40) Descriptor: Amyloid beta A4 protein, Fab-bound IDE, heavy chain, ... Authors: McCord, L.M, Liang, W, Farcasanu, M, Scherpelz, K, Meredith, S.C, Koide, S, Tang, W.J. Deposit date: 2013-08-02 Release date: 2014-08-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.5007 Å) Cite: Crystal Structure Analysis of Fab-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Amyloid-Beta (1-40) To be Published
4MVL	Crystal structure of an engineered lipocalin (Anticalin H1GA) in complex with the Alzheimer amyloid peptide Abeta1-40 Descriptor: Beta-amyloid protein 40, Neutrophil gelatinase-associated lipocalin Authors: Eichinger, A, Skerra, A. Deposit date: 2013-09-24 Release date: 2015-08-12 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide. Biochem.J., 473, 2016
4MVI	Crystal structure of an engineered lipocalin (Anticalin US7) in complex with the Alzheimer amyloid peptide Abeta(1-40) Descriptor: Beta-amyloid protein 40, Neutrophil gelatinase-associated lipocalin Authors: Eichinger, A, Skerra, A. Deposit date: 2013-09-24 Release date: 2015-08-12 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide. Biochem.J., 473, 2016
4NGE	Crystal Structure of Human Presequence Protease in Complex with Amyloid-beta (1-40) Descriptor: ACETATE ION, Beta-amyloid protein 40, GLYCEROL, ... Authors: King, J.V, Liang, W.G, Tang, W.J. Deposit date: 2013-11-01 Release date: 2014-05-14 Last modified: 2014-07-23 Method: X-RAY DIFFRACTION (2.704 Å) Cite: Molecular basis of substrate recognition and degradation by human presequence protease. Structure, 22, 2014
2MJ1	NMR structure of the soluble A beta 17-34 peptide Descriptor: Amyloid beta A4 protein Authors: Fonar, G, Samson, A.O. Deposit date: 2013-12-23 Release date: 2014-11-05 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: NMR structure of the water soluble A beta 17-34 peptide. Biosci.Rep., 34, 2014
4ONG	Fab fragment of 3D6 in complex with amyloid beta 1-40 Descriptor: 3D6 FAB ANTIBODY HEAVY CHAIN, 3D6 FAB ANTIBODY LIGHT CHAIN, Amyloid beta A4 protein, ... Authors: Feinberg, H, Saldanha, J.W, Diep, L, Goel, A, Widom, A, Veldman, G.M, Weis, W.I, Schenk, D, Basi, G.S. Deposit date: 2014-01-28 Release date: 2014-06-11 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure reveals conservation of amyloid-beta conformation recognized by 3D6 following humanization to bapineuzumab. Alzheimers Res Ther, 6, 2014
2MPZ	Atomic model of the Abeta D23N "Iowa" mutant using solid-state NMR, EM and Rosetta modeling Descriptor: Amyloid beta A4 protein Authors: Sgourakis, N.G, Qiang, W. Deposit date: 2014-06-10 Release date: 2015-04-22 Last modified: 2024-05-01 Method: SOLID-STATE NMR Cite: Modeling an in-register, parallel "iowa" a beta fibril structure using solid-state NMR data from labeled samples with rosetta. Structure, 23, 2015
2MVX	Atomic-resolution 3D structure of amyloid-beta fibrils: the Osaka mutation Descriptor: Amyloid beta A4 protein Authors: Schuetz, A.K, Vagt, T, Huber, M, Ovchinnikova, O.Y, Cadalbert, R, Wall, J, Guentert, P, Bockmann, A, Glockshuber, R, Meier, B.H. Deposit date: 2014-10-17 Release date: 2014-11-26 Last modified: 2024-05-01 Method: SOLID-STATE NMR Cite: Atomic-Resolution Three-Dimensional Structure of Amyloid beta Fibrils Bearing the Osaka Mutation. Angew.Chem.Int.Ed.Engl., 54, 2015
2MXU	42-Residue Beta Amyloid Fibril Descriptor: Amyloid beta A4 protein Authors: Xiao, Y, Ma, B, McElheny, D, Parthasarathy, S, Long, F, Hoshi, M, Nussinov, R, Ishii, Y. Deposit date: 2015-01-14 Release date: 2015-05-06 Last modified: 2024-05-01 Method: SOLID-STATE NMR Cite: A beta (1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease. Nat.Struct.Mol.Biol., 22, 2015
4XXD	Crystal Structure of mid-region amyloid beta capture by solanezumab Descriptor: Amyloid-beta fragment, Fab Heavy Chain, Fab Light Chain Authors: Hermans, S.J, Crespi, G.A.N, Parker, M.W, Miles, L.A. Deposit date: 2015-01-30 Release date: 2015-04-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Molecular basis for mid-region amyloid-beta capture by leading Alzheimer's disease immunotherapies. Sci Rep, 5, 2015
5BUO	A receptor molecule Descriptor: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ACETATE ION, Amyloid beta A4 protein, ... Authors: Gao, C, Crespi, G.A.N, Gorman, M.A, Nero, T.L, Parker, M.W, Miles, L.A. Deposit date: 2015-06-04 Release date: 2016-07-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.31 Å) Cite: NULL To Be Published
5AEF	Electron cryo-microscopy of an Abeta(1-42)amyloid fibril Descriptor: AMYLOID BETA A4 PROTEIN Authors: Schmidt, M, Rohou, A, Lasker, K, Yadav, J.K, Schiene-Fischer, C, Fandrich, M, Grigorieff, N. Deposit date: 2015-08-29 Release date: 2015-10-14 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (5 Å) Cite: Peptide Dimer Structure in an Abeta(1-42) Fibril Visualized with Cryo-Em Proc.Natl.Acad.Sci.USA, 112, 2015
2NAO	Atomic resolution structure of a disease-relevant Abeta(1-42) amyloid fibril Descriptor: Beta-amyloid protein 42 Authors: Waelti, M.A, Ravotti, F, Arai, H, Glabe, C, Wall, J, Bockmann, A, Guntert, P, Meier, B.H, Riek, R. Deposit date: 2016-01-07 Release date: 2016-07-27 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Atomic-resolution structure of a disease-relevant A beta (1-42) amyloid fibril. Proc.Natl.Acad.Sci.USA, 113, 2016
5HOX	X-ray crystallographic structure of an A-beta 17_36 beta-hairpin. Synchrotron data set. (LVFFAEDCGSNKCAII(SAR)LMV). Descriptor: Amyloid beta A4 protein, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500) Authors: Kreutzer, A.G, Nowick, J.S, Spencer, R.K. Deposit date: 2016-01-19 Release date: 2016-03-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: X-ray Crystallographic Structures of a Trimer, Dodecamer, and Annular Pore Formed by an A beta 17-36 beta-Hairpin. J.Am.Chem.Soc., 138, 2016
5HOW	X-ray crystallographic structure of an Abeta 17-36 beta-hairpin. LV(PHI)FAEDCGSNKCAII(SAR)L(ORN)V Descriptor: Amyloid beta A4 protein Authors: Kreutzer, A.G, Nowick, J.S, Spencer, R.K. Deposit date: 2016-01-19 Release date: 2016-03-23 Last modified: 2019-12-25 Method: X-RAY DIFFRACTION (2.295 Å) Cite: X-ray Crystallographic Structures of a Trimer, Dodecamer, and Annular Pore Formed by an A beta 17-36 beta-Hairpin. J.Am.Chem.Soc., 138, 2016
5HOY	X-ray crystallographic structure of an A-beta 17_36 beta-hairpin. X-ray diffractometer data set. (LVFFAEDCGSNKCAII(SAR)LMV). Descriptor: Amyloid beta A4 protein, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500) Authors: Kreutzer, A.G, Spencer, R.K, Nowick, J.S. Deposit date: 2016-01-19 Release date: 2016-03-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.295 Å) Cite: X-ray Crystallographic Structures of a Trimer, Dodecamer, and Annular Pore Formed by an A beta 17-36 beta-Hairpin. J.Am.Chem.Soc., 138, 2016
5KK3	Atomic Resolution Structure of Monomorphic AB42 Amyloid Fibrils Descriptor: Beta-amyloid protein 42 Authors: Colvin, M.T, Silvers, R, Zhe Ni, Q, Can, T.V, Sergeyev, I, Rosay, M, Donovan, K.J, Michael, B, Wall, J, Linse, S, Griffin, R.G. Deposit date: 2016-06-20 Release date: 2016-07-13 Last modified: 2024-05-01 Method: SOLID-STATE NMR Cite: Atomic Resolution Structure of Monomorphic A beta 42 Amyloid Fibrils. J.Am.Chem.Soc., 138, 2016

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