5AEF

Electron cryo-microscopy of an Abeta(1-42)amyloid fibril

Summary for 5AEF

EMDB information3132
DescriptorAMYLOID BETA A4 PROTEIN (1 entity in total)
Functional Keywordsprotein fibril, alzheimer's disease, amyloid fibril, protein aggregation, protein folding, cross-beta, frealix
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains2
Total molecular weight5670.73
Authors
Schmidt, M.,Rohou, A.,Lasker, K.,Yadav, J.K.,Schiene-Fischer, C.,Fandrich, M.,Grigorieff, N. (deposition date: 2015-08-29, release date: 2015-10-14, Last modification date: 2019-10-23)
Primary citation
Schmidt, M.,Rohou, A.,Lasker, K.,Yadav, J.K.,Schiene-Fischer, C.,Fandrich, M.,Grigorie, N.
Peptide Dimer Structure in an Abeta(1-42) Fibril Visualized with Cryo-Em
Proc.Natl.Acad.Sci.USA, 112:11858-, 2015
PubMed: 26351699 (PDB entries with the same primary citation)
DOI: 10.1073/PNAS.1503455112
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY (5 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers280 11.8%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation report