2LZ4
Solution NMR structure of transmembrane domain of amyloid precursor protein V44M
Summary for 2LZ4
Entry DOI | 10.2210/pdb2lz4/pdb |
Related | 2LZ3 |
NMR Information | BMRB: 18648 |
Descriptor | Amyloid beta A4 protein (1 entity in total) |
Functional Keywords | helix, dimer, transmembrane, membrane protein |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type I membrane protein: P05067 |
Total number of polymer chains | 2 |
Total formula weight | 6350.32 |
Authors | |
Primary citation | Chen, W.,Gamache, E.,Rosenman, D.J.,Xie, J.,Lopez, M.M.,Li, Y.M.,Wang, C. Familial Alzheimer's mutations within APPTM increase A beta 42 production by enhancing accessibility of epsilon-cleavage site. Nat Commun, 5:3037-3037, 2014 Cited by PubMed: 24390130DOI: 10.1038/ncomms4037 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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