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PDB: 5 results

4XXD
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BU of 4xxd by Molmil
Crystal Structure of mid-region amyloid beta capture by solanezumab
Descriptor: Amyloid-beta fragment, Fab Heavy Chain, Fab Light Chain
Authors:Hermans, S.J, Crespi, G.A.N, Parker, M.W, Miles, L.A.
Deposit date:2015-01-30
Release date:2015-04-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Molecular basis for mid-region amyloid-beta capture by leading Alzheimer's disease immunotherapies.
Sci Rep, 5, 2015
4HIX
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BU of 4hix by Molmil
Crystal structure of a humanised 3D6 Fab bound to amyloid beta peptide
Descriptor: Beta-amyloid protein 40, Humanized 3D6 Fab heavy chain, Humanized 3D6 Fab light chain
Authors:Miles, L.A, Crespi, G.A.N, Parker, M.W.
Deposit date:2012-10-12
Release date:2013-03-13
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation.
Sci Rep, 3, 2013
4OJF
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BU of 4ojf by Molmil
Humanised 3D6 Fab complexed to amyloid beta 1-8
Descriptor: Amyloid beta A4 protein, Humanised 3D6 Fab Heavy Chain, Humanised 3D6 Fab Light Chain
Authors:Miles, L.A, Crespi, G.A.N, Parker, M.W.
Deposit date:2014-01-21
Release date:2015-01-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Crystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer's disease immunotherapy candidate bapineuzumab complexed with amyloid-beta
ACTA CRYSTALLOGR.,SECT.F, 70, 2014
3U0W
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BU of 3u0w by Molmil
AD related murine antibody Fragment
Descriptor: Fab Heavy Chain, Ig gamma-1 chain C region, Fab Light Chain, ...
Authors:Miles, L.A, Crespi, G.A.N, Parker, M.W.
Deposit date:2011-09-29
Release date:2012-10-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of an AD related antibody
To be Published
5BUO
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BU of 5buo by Molmil
A receptor molecule
Descriptor: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ACETATE ION, Amyloid beta A4 protein, ...
Authors:Gao, C, Crespi, G.A.N, Gorman, M.A, Nero, T.L, Parker, M.W, Miles, L.A.
Deposit date:2015-06-04
Release date:2016-07-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:NULL
To Be Published

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