2M4J
40-residue beta-amyloid fibril derived from Alzheimer's disease brain
Summary for 2M4J
| Entry DOI | 10.2210/pdb2m4j/pdb |
| NMR Information | BMRB: 19009 |
| Descriptor | Amyloid beta A4 protein (1 entity in total) |
| Functional Keywords | amyloid, alzheimer's disease, solid state nmr, protein fibril |
| Biological source | Homo sapiens (human) |
| Cellular location | Membrane; Single-pass type I membrane protein: P05067 |
| Total number of polymer chains | 9 |
| Total formula weight | 39022.67 |
| Authors | Lu, J.,Qiang, W.,Meredith, S.C.,Yau, W.,Schweiters, C.D.,Tycko, R. (deposition date: 2013-02-05, release date: 2013-09-25, Last modification date: 2023-06-14) |
| Primary citation | Lu, J.X.,Qiang, W.,Yau, W.M.,Schwieters, C.D.,Meredith, S.C.,Tycko, R. Molecular Structure of beta-Amyloid Fibrils in Alzheimer's Disease Brain Tissue. Cell(Cambridge,Mass.), 154:1257-1268, 2013 Cited by PubMed: 24034249DOI: 10.1016/j.cell.2013.08.035 PDB entries with the same primary citation |
| Experimental method | SOLID-STATE NMR |
Structure validation
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